Rn01640372_m1 Best Coverage

• Gene Symbol: Esr1
• Gene Name: estrogen receptor 1
• Gene Aliases: ER-alpha, Esr, RNESTROR
• Chromosome Location: Chr.1: 41192150 - 41594799 on Build Rnor_6.0
• Species: Rat
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Esr1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_012689.1	NP_036821.1	6 - 7	1458		67
	XM_006227832.2	XP_006227894.1	6 - 7	2058		67
	XM_008758703.1	XP_008756925.1	7 - 8	2106		67
	XM_008758704.1	XP_008756926.1	6 - 7	2030		67
GenBank mRNA	AB477039.1	-	6 - 7	1464		67
	GU111761.1	-	2 - 3	215		67
	X61098.1	-	5 - 6	1322		67
	Y00102.1	-	6 - 7	1458		67

More Information

Updated Mapping Information

This assay targets the same location as RTA transcript cluster(s) TC0100000418.rn.1

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Nuclear Receptor, Recommended Assay, Rattus norvegicus, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Esr1

Gene Ontology Categories:

Process(es)

antral ovarian follicle growth
epithelial cell development
osteoblast development
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
phospholipase C-activating G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
androgen metabolic process
male gonad development
negative regulation of gene expression
positive regulation of phospholipase C activity
intracellular steroid hormone receptor signaling pathway
intracellular estrogen receptor signaling pathway
intracellular receptor signaling pathway
response to estradiol
regulation of apoptotic process
negative regulation of I-kappaB kinase/NF-kappaB signaling
steroid hormone mediated signaling pathway
negative regulation of sequence-specific DNA binding transcription factor activity
regulation of neuron apoptotic process
response to estrogen
positive regulation of nitric oxide biosynthetic process
positive regulation of epidermal growth factor receptor signaling pathway
positive regulation of transcription from RNA polymerase II promoter
negative regulation of glucose import
decidualization
positive regulation of fibroblast proliferation
positive regulation of retinoic acid receptor signaling pathway
negative regulation of smooth muscle cell proliferation
positive regulation of nitric-oxide synthase activity
positive regulation of sequence-specific DNA binding transcription factor activity
Sertoli cell development
Sertoli cell proliferation
uterus development
vagina development
prostate epithelial cord elongation
prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis
regulation of branching involved in prostate gland morphogenesis
mammary gland branching involved in pregnancy
mammary gland alveolus development
epithelial cell proliferation involved in mammary gland duct elongation
positive regulation of ERK1 and ERK2 cascade
cellular response to estrogen stimulus
cellular response to estradiol stimulus
negative regulation of triglyceride metabolic process
negative regulation of neuron death
baculum development

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
core promoter sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
steroid hormone receptor activity
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
steroid binding
protein binding
beta-catenin binding
transcription factor binding
zinc ion binding
enzyme binding
estrogen receptor activity
type 1 metabotropic glutamate receptor binding
protein complex binding
estrogen response element binding
RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
hormone binding
identical protein binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Rat Clariom S Assay	PSR0100002568.rn.1	TC0100000418.rn.1	RTA TC