100821

• Gene Symbol: Cbs
• Gene Name: cystathionine beta-synthase
• Gene Aliases: AI047524, AI303044, HIP4
• Chromosome Location: Chr.17: 31612623 - 31637233 on Build GRCm38
• UniGene ID: Mm.206417
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Cbs
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001271353.1	NP_001258282.1	5	729
	NM_144855.3	NP_659104.1	5	732
	NM_178224.3	NP_835742.1	5	732
GenBank mRNA	AK077669.1	-	5	693
	AK085692.1	-	5	694
	BC013472.1	-	5	658	4221477
	BC013480.1	-	5	668	4239757
	BC022144.1	-	5	693
	BC026595.1	-	5	665	4974777

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_012522, M88347, M88345, M88344, FQ211441, and others.

Panther Classification:

Molecular Function -

lyase, metabolite interconversion enzyme

Gene Ontology Categories:

Process(es)

endochondral ossification
blood vessel remodeling
cysteine biosynthetic process from serine
superoxide metabolic process
cellular amino acid biosynthetic process
cysteine biosynthetic process via cystathionine
cysteine biosynthetic process
transsulfuration
cerebellum morphogenesis
regulation of cGMP metabolic process
negative regulation of apoptotic process
regulation of JUN kinase activity
homocysteine metabolic process
regulation of blood vessel size
response to folic acid
oxidation-reduction process
maternal process involved in female pregnancy
cartilage development involved in endochondral bone morphogenesis
hydrogen sulfide biosynthetic process
cellular response to hypoxia

Function(s)

cystathionine beta-synthase activity
lyase activity
oxygen binding
enzyme binding
heme binding
pyridoxal phosphate binding
ubiquitin protein ligase binding
identical protein binding
protein homodimerization activity
metal ion binding
nitrite reductase (NO-forming) activity
carbon monoxide binding
nitric oxide binding
modified amino acid binding
S-adenosyl-L-methionine binding