101824

• Gene Symbol: Ins2
• Gene Name: insulin II
• Gene Aliases: AA986540, Ins-2, InsII, Mody, Mody4, proinsulin
• Chromosome Location: Chr.7: 142678656 - 142679708 on Build GRCm38
• UniGene ID: Mm.4946
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Ins2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001185083.1	NP_001172012.1	2	150
	NM_001185084.1	NP_001172013.1	1	264
	NM_008387.4	NP_032413.1	2	162
GenBank mRNA	AK007612.1	-	2	163
	AY899305.1	-	1	229
	BC066208.1	-	2	127
	BC099934.1	-	2	135	6432976
	BC132650.1	-	2	135	40130927
	BC132652.1	-	2	135	40130929
	BC145554.1	-	2	123	9054118
	GQ915612.1	-	2	150

More Information

Panther Classification:

Molecular Function -

growth factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
MAPK cascade
activation of MAPK activity
negative regulation of acute inflammatory response
carbohydrate metabolic process
glucose metabolic process
regulation of cellular amino acid metabolic process
acute-phase response
ER overload response
G-protein coupled receptor signaling pathway
activation of JUN kinase activity
myoblast fusion
positive regulation of cell proliferation
insulin receptor signaling pathway
regulation of gene expression
positive regulation of phosphatidylinositol 3-kinase signaling
myotube differentiation
glucose transport
lipid catabolic process
regulation of transmembrane transporter activity
activation of protein kinase B activity
positive regulation of cellular protein metabolic process
negative regulation of protein oligomerization
regulation of protein localization
negative regulation of NAD(P)H oxidase activity
wound healing
negative regulation of protein catabolic process
regulation of phosphorylation
glucose homeostasis
regulation of protein binding
positive regulation of MAPK cascade
positive regulation of phosphatidylinositol 3-kinase activity
positive regulation of glycogen biosynthetic process
positive regulation of DNA replication
negative regulation of glycogen catabolic process
positive regulation of glycolytic process
positive regulation of mitotic nuclear division
negative regulation of proteolysis
negative regulation of fatty acid metabolic process
positive regulation of glucose import
positive regulation of insulin receptor signaling pathway
alpha-beta T cell activation
regulation of protein secretion
negative regulation of protein secretion
positive regulation of cytokine secretion
positive regulation of peptidyl-tyrosine phosphorylation
negative regulation of lipid catabolic process
positive regulation of NF-kappaB transcription factor activity
positive regulation of protein kinase B signaling
fatty acid homeostasis
canonical Wnt signaling pathway
negative regulation of respiratory burst involved in inflammatory response
positive regulation of respiratory burst
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
positive regulation of protein localization to nucleus
negative regulation of feeding behavior

Function(s)

protease binding
insulin receptor binding
insulin-like growth factor receptor binding
hormone activity
protein complex binding
identical protein binding