103331 Validated

• Gene Symbol: ERBB4
• Gene Name: erb-b2 receptor tyrosine kinase 4
• Gene Aliases: ALS19, HER4, p180erbB4
• Chromosome Location: Chr.2: 211375717 - 212539147 on Build GRCh38
• UniGene ID: Hs.390729
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: ERBB4
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001042599.1	NP_001036064.1	3	442
	NM_005235.2	NP_005226.1	3	442
	XM_005246376.2	XP_005246433.1	3	961
	XM_005246377.2	XP_005246434.1	3	961
	XM_006712364.2	XP_006712427.1	3	961
	XM_017003577.1	XP_016859066.1	3	961
	XM_017003578.1	XP_016859067.1	3	961
	XM_017003579.1	XP_016859068.1	3	961
	XM_017003580.1	XP_016859069.1	3	961
	XM_017003581.1	XP_016859070.1	3	961
GenBank mRNA	AK308606.1	-	3	398
	BC112199.1	-	3	383	8327667
	BC143741.1	-	3	371	9052255
	BC143747.1	-	3	371	9052261
	BC143749.1	-	3	371	9052263
	L07868.1	-	3	377

More Information

Matching Taqman Gene Expression Assay:

Hs00171783_m1

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

MAPK cascade
neural crest cell migration
positive regulation of protein phosphorylation
transcription, DNA-templated
signal transduction
transmembrane receptor protein tyrosine kinase signaling pathway
nervous system development
heart development
lactation
cell proliferation
positive regulation of cell proliferation
negative regulation of cell proliferation
embryonic pattern specification
regulation of phosphatidylinositol 3-kinase signaling
positive regulation of phosphatidylinositol 3-kinase signaling
cell migration
peptidyl-tyrosine phosphorylation
central nervous system morphogenesis
olfactory bulb interneuron differentiation
regulation of cell migration
ERBB2 signaling pathway
positive regulation of tyrosine phosphorylation of Stat5 protein
positive regulation of GTPase activity
mitochondrial fragmentation involved in apoptotic process
cell fate commitment
positive regulation of transcription, DNA-templated
protein autophosphorylation
phosphatidylinositol phosphorylation
phosphatidylinositol-mediated signaling
positive regulation of cardiac muscle cell proliferation
mammary gland epithelial cell differentiation
mammary gland alveolus development
cardiac muscle tissue regeneration
positive regulation of ERK1 and ERK2 cascade
positive regulation of protein localization to cell surface
regulation of cell motility
positive regulation of STAT protein import into nucleus
negative regulation of neuron migration

Function(s)

protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
receptor signaling protein tyrosine kinase activity
Ras guanyl-nucleotide exchange factor activity
epidermal growth factor receptor binding
protein binding
ATP binding
protein homodimerization activity
transcription regulatory region DNA binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity