103417

• Gene Symbol: SRC
• Gene Name: SRC proto-oncogene, non-receptor tyrosine kinase
• Gene Aliases: ASV, SRC1, THC6, c-SRC, p60-Src
• Chromosome Location: Chr.20: 37344685 - 37405432 on Build GRCh38
• UniGene ID: Hs.195659
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: SRC
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_005417.4	NP_005408.1	10	1402
	NM_198291.2	NP_938033.1	10	1327
	XM_011529013.2	XP_011527315.1	11	1671
	XM_017028024.1	XP_016883513.1	12	1695
	XM_017028025.1	XP_016883514.1	11	1576
	XM_017028026.1	XP_016883515.1	11	1415
	XM_017028027.1	XP_016883516.1	9	992
GenBank mRNA	AK024281.1	-	3	599
	BC011566.1	-	8	992	4548399
	BC051270.1	-	8	1055	4871614

More Information

Gene Ontology Categories:

Process(es)

stimulatory C-type lectin receptor signaling pathway
cell cycle
signal transduction
signal complex assembly
epidermal growth factor receptor signaling pathway
transforming growth factor beta receptor signaling pathway
integrin-mediated signaling pathway
central nervous system development
cell proliferation
response to mechanical stimulus
response to virus
response to acidic pH
regulation of epithelial cell migration
positive regulation of epithelial cell migration
positive regulation of platelet-derived growth factor receptor signaling pathway
positive regulation of glucose metabolic process
positive regulation of smooth muscle cell migration
single organismal cell-cell adhesion
peptidyl-serine phosphorylation
peptidyl-tyrosine phosphorylation
regulation of cell-cell adhesion
platelet activation
intracellular estrogen receptor signaling pathway
forebrain development
T cell costimulation
protein destabilization
response to nutrient levels
positive regulation of protein autophosphorylation
activation of protein kinase B activity
negative regulation of telomere maintenance via telomerase
negative regulation of protein homooligomerization
cellular response to insulin stimulus
regulation of intracellular estrogen receptor signaling pathway
positive regulation of integrin activation
adherens junction organization
substrate adhesion-dependent cell spreading
cellular response to reactive oxygen species
intracellular signal transduction
osteoclast development
cellular response to platelet-derived growth factor stimulus
peptidyl-tyrosine autophosphorylation
Fc-gamma receptor signaling pathway involved in phagocytosis
ERBB2 signaling pathway
regulation of cell proliferation
response to drug
response to hydrogen peroxide
positive regulation of apoptotic process
negative regulation of apoptotic process
regulation of vascular permeability
stress fiber assembly
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
regulation of protein binding
positive regulation of MAP kinase activity
positive regulation of phosphatidylinositol 3-kinase activity
transcytosis
innate immune response
regulation of bone resorption
bone resorption
positive regulation of cyclin-dependent protein serine/threonine kinase activity
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of insulin receptor signaling pathway
protein autophosphorylation
platelet-derived growth factor receptor signaling pathway
vascular endothelial growth factor receptor signaling pathway
neurotrophin TRK receptor signaling pathway
ephrin receptor signaling pathway
oogenesis
positive regulation of cytokine secretion
positive regulation of peptidyl-tyrosine phosphorylation
progesterone receptor signaling pathway
leukocyte migration
positive regulation of small GTPase mediated signal transduction
response to mineralocorticoid
response to electrical stimulus
regulation of cell cycle
negative regulation of focal adhesion assembly
positive regulation of protein kinase B signaling
negative regulation of mitochondrial depolarization
negative regulation of telomerase activity
uterus development
branching involved in mammary gland duct morphogenesis
regulation of cell projection assembly
positive regulation of ERK1 and ERK2 cascade
response to interleukin-1
cellular response to lipopolysaccharide
cellular response to peptide hormone stimulus
cellular response to progesterone stimulus
cellular response to fatty acid
cellular response to hypoxia
cellular response to fluid shear stress
regulation of podosome assembly
positive regulation of podosome assembly
positive regulation of protein serine/threonine kinase activity
angiotensin-activated signaling pathway involved in heart process
positive regulation of canonical Wnt signaling pathway
positive regulation of lamellipodium morphogenesis
positive regulation of DNA biosynthetic process
regulation of early endosome to late endosome transport
negative regulation of anoikis
negative regulation of extrinsic apoptotic signaling pathway
negative regulation of intrinsic apoptotic signaling pathway
regulation of caveolin-mediated endocytosis

Function(s)

protein kinase activity
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
SH3/SH2 adaptor activity
protein kinase C binding
receptor binding
insulin receptor binding
integrin binding
protein binding
ATP binding
protein C-terminus binding
kinase activity
enzyme binding
kinase binding
heme binding
estrogen receptor binding
SH2 domain binding
ion channel binding
ephrin receptor binding
phosphoprotein binding
hormone receptor binding
growth factor receptor binding
scaffold protein binding
cadherin binding involved in cell-cell adhesion