105550 Validated

• Gene Symbol: PSEN2
• Gene Name: presenilin 2
• Gene Aliases: AD3L, AD4, CMD1V, PS2, STM2
• Chromosome Location: Chr.1: 226870572 - 226903829 on Build GRCh38
• UniGene ID: Hs.25363
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: PSEN2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000447.2	NP_000438.2	5	667
	NM_012486.2	NP_036618.2	5	667
	XM_005273199.3	XP_005273256.1	4	480
	XM_017001835.1	XP_016857324.1	4	988
	XM_017001836.1	XP_016857325.1	4	480
GenBank mRNA	AF416718.1	-	3	308
	AK292299.1	-	6	619
	AK301143.1	-	4	416
	BC006365.2	-	6	861	4131408
	BT006984.1	-	3	240
	DA915823.1	-	5	620
	L43964.1	-	4	607
	L44577.1	-	5	605
	U34349.1	-	3	331

More Information

Matching Taqman Gene Expression Assay:

Hs01577197_m1

Panther Classification:

Molecular Function -

aspartic protease

Gene Ontology Categories:

Process(es)

response to hypoxia
membrane protein ectodomain proteolysis
calcium ion transport
Notch signaling pathway
Notch receptor processing
protein processing
membrane protein intracellular domain proteolysis
intracellular signal transduction
amyloid precursor protein catabolic process
positive regulation of apoptotic process
negative regulation of apoptotic process
positive regulation of catalytic activity
ephrin receptor signaling pathway
beta-amyloid metabolic process

Function(s)

endopeptidase activity
aspartic-type endopeptidase activity
protein binding