105635

• Gene Symbol: CFLAR
• Gene Name: CASP8 and FADD like apoptosis regulator
• Gene Aliases: CASH, CASP8AP1, CLARP, Casper, FLAME, FLAME-1, FLAME1, FLIP, I-FLICE, MRIT, c-FLIP, c-FLIPL, c-FLIPR, c-FLIPS
• Chromosome Location: Chr.2: 201116015 - 201172688 on Build GRCh38
• UniGene ID: Hs.390736
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: CFLAR
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001127183.2	NP_001120655.1	2	641
	NM_001127184.2	NP_001120656.1	2	613
	NM_001202516.1	NP_001189445.1	2	613
	NM_001308042.1	NP_001294971.1	1	285
	NM_001308043.1	NP_001294972.1	2	663
	NM_003879.5	NP_003870.4	2	613
	XM_017005189.1	XP_016860678.1	2	604
	XM_017005190.1	XP_016860679.1	2	477
	XM_017005191.1	XP_016860680.1	2	556
	XM_017005192.1	XP_016860681.1	2	604
	XM_017005193.1	XP_016860682.1	2	2621
	XM_017005194.1	XP_016860683.1	2	477
	XM_017005195.1	XP_016860684.1	2	594
	XM_017005197.1	XP_016860686.1	2	2621
	XM_017005198.1	XP_016860687.1	2	477
GenBank mRNA	AB209600.1	-	2	360
	AF005774.1	-	2	583
	AF005775.1	-	1	148
	AF009616.1	-	2	560
	AF009617.1	-	1	148
	AF009618.1	-	1	148
	AF009619.1	-	1	148
	AF010127.1	-	2	558
	AF015450.1	-	2	652
	AF015451.1	-	1	148
	AF015452.1	-	1	148
	AF041458.1	-	1	163
	AF041460.1	-	1	148
	AF041461.1	-	1	103
	AK289913.1	-	2	437
	AK297387.1	-	2	603
	AK308767.1	-	2	523
	AK315208.1	-	2	384
	BC001602.1	-	2	407	3542993
	BT006751.1	-	1	148
	BX457155.2	-	2	630
	U85059.1	-	1	148
	U97074.1	-	2	530
	U97075.1	-	1	441
	Y14039.1	-	2	629
	Y14040.1	-	2	629

More Information

Panther Classification:

Molecular Function -

protease

Gene Ontology Categories:

Process(es)

proteolysis
apoptotic process
skeletal muscle tissue development
skeletal muscle atrophy
regulation of skeletal muscle satellite cell proliferation
skeletal myofibril assembly
viral process
negative regulation of apoptotic process
positive regulation of catalytic activity
positive regulation of I-kappaB kinase/NF-kappaB signaling
skeletal muscle tissue regeneration
positive regulation of NF-kappaB transcription factor activity
regulation of necroptotic process
execution phase of apoptosis
negative regulation of myoblast fusion
regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of extrinsic apoptotic signaling pathway

Function(s)

protease binding
death receptor binding
protein binding
enzyme activator activity
protein complex binding
cysteine-type endopeptidase activity involved in execution phase of apoptosis