105636

• Gene Symbol: CFLAR
• Gene Name: CASP8 and FADD like apoptosis regulator
• Gene Aliases: CASH, CASP8AP1, CLARP, Casper, FLAME, FLAME-1, FLAME1, FLIP, I-FLICE, MRIT, c-FLIP, c-FLIPL, c-FLIPR, c-FLIPS
• Chromosome Location: Chr.2: 201116015 - 201172688 on Build GRCh38
• UniGene ID: Hs.390736
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: CFLAR
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001127183.2	NP_001120655.1	2	683
	NM_001127184.2	NP_001120656.1	2	655
	NM_001202516.1	NP_001189445.1	2	655
	NM_001308042.1	NP_001294971.1	1	327
	NM_001308043.1	NP_001294972.1	2	705
	NM_003879.5	NP_003870.4	2	655
	XM_017005189.1	XP_016860678.1	2	646
	XM_017005190.1	XP_016860679.1	2	519
	XM_017005191.1	XP_016860680.1	2	598
	XM_017005192.1	XP_016860681.1	2	646
	XM_017005193.1	XP_016860682.1	2	2663
	XM_017005194.1	XP_016860683.1	2	519
	XM_017005195.1	XP_016860684.1	2	636
	XM_017005197.1	XP_016860686.1	2	2663
	XM_017005198.1	XP_016860687.1	2	519
GenBank mRNA	AB209600.1	-	2	402
	AF005774.1	-	2	625
	AF005775.1	-	1	190
	AF009616.1	-	2	602
	AF009617.1	-	1	190
	AF009618.1	-	1	190
	AF009619.1	-	1	190
	AF010127.1	-	2	600
	AF015450.1	-	2	694
	AF015451.1	-	1	190
	AF015452.1	-	1	190
	AF041458.1	-	1	205
	AF041460.1	-	1	190
	AF041461.1	-	1	145
	AK289913.1	-	2	479
	AK308767.1	-	2	565
	AK315208.1	-	2	426
	BC001602.1	-	2	449	3542993
	BT006751.1	-	1	190
	BX457155.2	-	2	672
	U85059.1	-	1	190
	U97074.1	-	2	572
	U97075.1	-	1	483
	Y14039.1	-	2	671
	Y14040.1	-	2	671

More Information

Panther Classification:

Molecular Function -

protease

Gene Ontology Categories:

Process(es)

proteolysis
apoptotic process
skeletal muscle tissue development
skeletal muscle atrophy
regulation of skeletal muscle satellite cell proliferation
skeletal myofibril assembly
viral process
negative regulation of apoptotic process
positive regulation of catalytic activity
positive regulation of I-kappaB kinase/NF-kappaB signaling
skeletal muscle tissue regeneration
positive regulation of NF-kappaB transcription factor activity
regulation of necroptotic process
execution phase of apoptosis
negative regulation of myoblast fusion
regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of extrinsic apoptotic signaling pathway

Function(s)

protease binding
death receptor binding
protein binding
enzyme activator activity
protein complex binding
cysteine-type endopeptidase activity involved in execution phase of apoptosis