106725 Validated

• Gene Symbol: ITGA2
• Gene Name: integrin subunit alpha 2
• Gene Aliases: BR, CD49B, GPIa, HPA-5, VLA-2, VLAA2
• Chromosome Location: Chr.5: 52989326 - 53094779 on Build GRCh38
• UniGene ID: Hs.482077
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: ITGA2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_002203.3	NP_002194.2	10	1262
	NR_073103.1		10	1262
	NR_073104.1		10	1262
	NR_073105.1		10	1262
	NR_073106.1		10	1262
	NR_073107.1		9	1141
GenBank mRNA	AK307952.1	-	10	1251
	BC143505.1	-	10	1148
	BC143508.1	-	10	1148
	BC143509.1	-	10	1148
	BC143511.1	-	10	1148
	BC143512.1	-	9	1027
	BM828183.1	-	4	417
	X17033.1	-	10	1167

More Information

Matching Taqman Gene Expression Assay:

Hs00158148_m1

Panther Classification:

Molecular Function -

integrin

Gene Ontology Categories:

Process(es)

response to hypoxia
positive regulation of leukocyte migration
substrate-dependent cell migration
hypotonic response
cell adhesion
cell-matrix adhesion
integrin-mediated signaling pathway
female pregnancy
blood coagulation
cell proliferation
organ morphogenesis
positive regulation of epithelial cell migration
positive regulation of alkaline phosphatase activity
response to amine
response to muscle activity
positive regulation of smooth muscle cell migration
extracellular matrix organization
mammary gland development
positive regulation of cell projection organization
cell-substrate adhesion
positive regulation of collagen biosynthetic process
positive regulation of collagen binding
response to L-ascorbic acid
cell adhesion mediated by integrin
collagen-activated signaling pathway
response to drug
positive regulation of DNA binding
skin morphogenesis
establishment of protein localization
positive regulation of translation
positive regulation of cell adhesion
positive regulation of smooth muscle contraction
viral entry into host cell
focal adhesion assembly
mesodermal cell differentiation
positive regulation of smooth muscle cell proliferation
positive regulation of inflammatory response
positive regulation of positive chemotaxis
detection of mechanical stimulus involved in sensory perception of pain
positive regulation of transmission of nerve impulse
positive regulation of phagocytosis, engulfment
hepatocyte differentiation
response to parathyroid hormone
cellular response to mechanical stimulus
cellular response to estradiol stimulus

Function(s)

virus receptor activity
integrin binding
protein binding
collagen binding
protein complex binding
collagen receptor activity
laminin binding
metal ion binding
protein heterodimerization activity
collagen binding involved in cell-matrix adhesion