111172 Validated

• Gene Symbol: MGMT
• Gene Name: O-6-methylguanine-DNA methyltransferase
• Gene Aliases: -
• Chromosome Location: Chr.10: 129467184 - 129770983 on Build GRCh38
• UniGene ID: Hs.501522
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: MGMT
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_002412.4	NP_002403.2	5	784
	XM_005252682.2	XP_005252739.1	5	821
	XM_017016275.1	XP_016871764.1	4	607
GenBank mRNA	AK293593.1	-	5	754
	BC000824.1	-	5	712	3454207
	M29971.1	-	5	755
	M31767.1	-	4	681
	M60761.1	-	4	674
	X54228.1	-	4	699

More Information

Matching Taqman Gene Expression Assay:

Hs00172470_m1

Gene Ontology Categories:

Process(es)

DNA ligation
DNA methylation
DNA dealkylation involved in DNA repair
response to toxic substance
cellular response to oxidative stress
response to drug
negative regulation of apoptotic process
regulation of cysteine-type endopeptidase activity involved in apoptotic process
response to ethanol
response to folic acid
mammary gland epithelial cell differentiation
cellular response to organic cyclic compound
cellular response to ionizing radiation
positive regulation of double-strand break repair

Function(s)

DNA binding
damaged DNA binding
methylated-DNA-[protein]-cysteine S-methyltransferase activity
calcium ion binding
methyltransferase activity
DNA-methyltransferase activity