111380

• Gene Symbol: TNFRSF10B
• Gene Name: TNF receptor superfamily member 10b
• Gene Aliases: CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9
• Chromosome Location: Chr.8: 23020133 - 23069187 on Build GRCh38
• UniGene ID: Hs.521456
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: TNFRSF10B
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_003842.4	NP_003833.4	2	452
	NM_147187.2	NP_671716.2	2	452
GenBank mRNA	AB451272.1	-	2	159
	AB451399.1	-	2	159
	AF012535.1	-	2	298
	AF012628.1	-	2	159
	AF016266.1	-	2	276
	AF016268.1	-	2	268
	AF016849.1	-	2	303
	AF018657.1	-	2	159
	AF018658.1	-	2	159
	AF020501.1	-	2	159
	AF022386.1	-	2	159
	AF153687.1	-	2	277
	AF192548.1	-	2	259
	AK291216.1	-	2	279
	AL529460.3	-	2	452
	AY358277.1	-	2	298
	BC001281.1	-	2	306	3458466
	BX538104.1	-	2	292
	CR541898.1	-	2	159
	DA738472.1	-	2	452
	DA889488.1	-	2	296

More Information

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
inflammatory response
immune response
cell surface receptor signaling pathway
activation of NF-kappaB-inducing kinase activity
multicellular organism development
extrinsic apoptotic signaling pathway via death domain receptors
response to lipopolysaccharide
tumor necrosis factor-mediated signaling pathway
response to endoplasmic reticulum stress
regulation of cell proliferation
regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
cellular response to mechanical stimulus
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

Function(s)

receptor activity
tumor necrosis factor-activated receptor activity
protein binding
TRAIL binding