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Gene Symbol:
PSEN1
Gene Name:
presenilin 1
Gene Aliases:
AD3, FAD, PS-1, PS1, S182
Chromosome Location:
Chr.14: 73136435 - 73223691 on Build GRCh38
UniGene ID:
Hs.3260
Species:
Human
Species Specific ID (Flybase ID):
-
siRNA ID 112528

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Catalog # AM16708
Price 4,126.00
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4126.0
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  • Genomic Map
  • siRNA Details
  • More Information

Genomic Map

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siRNA Details

Gene Symbol: PSEN1
Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
RefSeq NM_000021.3 NP_000012.1 4 436
NM_007318.2 NP_015557.2 4 424
XM_005267864.2 XP_005267921.1 4 430
XM_005267866.1 XP_005267923.1 4 419
XM_011536971.2 XP_011535273.1 4 328
XM_011536972.2 XP_011535274.1 4 692
XM_011536973.1 XP_011535275.1 4 680
XM_011536974.1 XP_011535276.1 4 321
GenBank mRNA AF416717.1 - 2 152
AJ008005.1 - 4 370
AK122722.1 - 2 1705
AK223173.1 - 2 166
AK303876.1 - 4 408
AK312531.1 - 4 420
BC011729.2 - 4 405 4423098
DB203403.1 - 4 424
KU178285.1 - 2 140
KU178286.1 - 2 152
L42110.1 - 4 400
L76517.1 - 4 693
U40379.1 - 2 140
U40380.1 - 2 140

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More Information


Panther Classification:

Molecular Function -

aspartic protease

Gene Ontology Categories:

Function(s) Process(es)

autophagosome assembly
negative regulation of transcription from RNA polymerase II promoter
activation of MAPKK activity
blood vessel development
cell fate specification
somitogenesis
neuron migration
positive regulation of receptor recycling
heart looping
hematopoietic progenitor cell differentiation
T cell activation involved in immune response
neural retina development
protein glycosylation
membrane protein ectodomain proteolysis
mitochondrial transport
cellular response to DNA damage stimulus
response to oxidative stress
negative regulation of epidermal growth factor-activated receptor activity
Notch signaling pathway
Notch receptor processing
memory
post-embryonic development
protein transport
L-glutamate transport
choline transport
synaptic vesicle targeting
single organismal cell-cell adhesion
protein processing
cerebral cortex cell migration
Cajal-Retzius cell differentiation
dorsal/ventral neural tube patterning
embryonic limb morphogenesis
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
endoplasmic reticulum calcium ion homeostasis
beta-amyloid formation
intracellular signal transduction
regulation of phosphorylation
amyloid precursor protein catabolic process
myeloid dendritic cell differentiation
positive regulation of apoptotic process
negative regulation of apoptotic process
positive regulation of catalytic activity
regulation of protein binding
positive regulation of MAP kinase activity
negative regulation of neuron apoptotic process
skin morphogenesis
positive regulation of transcription, DNA-templated
regulation of synaptic plasticity
thymus development
neuron development
skeletal system morphogenesis
brain morphogenesis
epithelial cell proliferation
negative regulation of axonogenesis
positive regulation of coagulation
T cell receptor signaling pathway
neuron apoptotic process
negative regulation of ubiquitin-protein transferase activity
smooth endoplasmic reticulum calcium ion homeostasis
regulation of synaptic transmission, glutamatergic
canonical Wnt signaling pathway
regulation of resting membrane potential
positive regulation of dendritic spine development
calcium ion transmembrane transport
negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
negative regulation of apoptotic signaling pathway
endopeptidase activity
aspartic-type endopeptidase activity
calcium channel activity
protein binding
beta-catenin binding
PDZ domain binding
cadherin binding

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