117191

• Gene Symbol: TNKS
• Gene Name: tankyrase
• Gene Aliases: ARTD5, PARP-5a, PARP5A, PARPL, TIN1, TINF1, TNKS1, pART5
• Chromosome Location: Chr.8: 9555229 - 9782346 on Build GRCh38
• UniGene ID: Hs.370267
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: TNKS
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_003747.2	NP_003738.2	2	758
	XM_006716263.3	XP_006716326.1	2	1464
	XM_011543845.2	XP_011542147.1	2	1464
	XM_011543846.2	XP_011542148.1	2	1464
	XM_011543847.2	XP_011542149.1	2	1463
GenBank mRNA	AF082556.1	-	2	758
	AF082557.1	-	1	54
	AK301798.1	-	2	679
	AK302031.1	-	2	779
	AK302534.1	-	2	432
	BC098394.1	-	2	781	4374347

More Information

Panther Classification:

Molecular Function -

kinase inhibitor

Gene Ontology Categories:

Process(es)

protein polyubiquitination
protein ADP-ribosylation
mitotic spindle organization
mitotic nuclear division
protein transport
Wnt signaling pathway
peptidyl-serine phosphorylation
peptidyl-threonine phosphorylation
regulation of telomere maintenance via telomerase
positive regulation of telomere maintenance via telomerase
positive regulation of transcription from RNA polymerase II promoter
mRNA transport
spindle assembly
cell division
positive regulation of telomerase activity
protein localization to chromosome, telomeric region
protein poly-ADP-ribosylation
protein auto-ADP-ribosylation
positive regulation of canonical Wnt signaling pathway
positive regulation of telomere capping
negative regulation of telomere maintenance via telomere lengthening
negative regulation of telomeric DNA binding
negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric

Function(s)

NAD+ ADP-ribosyltransferase activity
protein binding
zinc ion binding
histone binding