119230

• Gene Symbol: ARHGEF2
• Gene Name: Rho/Rac guanine nucleotide exchange factor 2
• Gene Aliases: GEF, GEF-H1, GEFH1, LFP40, P40
• Chromosome Location: Chr.1: 155946839 - 155991263 on Build GRCh38
• UniGene ID: Hs.743352
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: ARHGEF2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001162383.1	NP_001155855.1	7	711
	NM_001162384.1	NP_001155856.1	6, 7	708
	NM_004723.3	NP_004714.2	6, 7	636
	XM_005245587.2	XP_005245644.1	7	764
	XM_005245588.2	XP_005245645.1	6, 7	761
	XM_005245589.4	XP_005245646.1	7	917
	XM_005245590.3	XP_005245647.1	7	639
	XM_005245591.3	XP_005245648.1	8	755
	XM_005245592.2	XP_005245649.1	7	908
	XM_005245593.4	XP_005245650.1	7	639
	XM_005245594.2	XP_005245651.1	7	1625
	XM_006711622.3	XP_006711685.1	7	1902
	XM_006711623.3	XP_006711686.1	6	638
	XM_006711624.3	XP_006711687.1	6	665
	XM_006711625.3	XP_006711688.1	6	571
	XM_006711626.2	XP_006711689.1	6	1557
	XM_011510136.2	XP_011508438.2	10, 11	1320
	XM_011510137.2	XP_011508439.2	11	1323
	XM_011510139.2	XP_011508441.1	11	1323
	XM_011510141.2	XP_011508443.1	7	1441
	XM_011510143.2	XP_011508445.1	3	187
	XM_017002794.1	XP_016858283.1	10, 11	1320
	XM_017002795.1	XP_016858284.1	6, 7	655
	XM_017002796.1	XP_016858285.1	6, 7	1899
	XM_017002797.1	XP_016858286.1	6, 7	639
	XM_017002798.1	XP_016858287.1	6	1834
	XM_017002799.1	XP_016858288.1	5, 6	635
GenBank mRNA	AB014551.3	-	10, 11	979
	AF486838.1	-	6, 7	590
	AK295924.1	-	7	908
	AK304548.1	-	10	1048
	AL512715.1	-	6, 7	621
	BC020567.1	-	7	693	4157775
	BT007407.1	-	6	512
	U72206.1	-	7	695

More Information

Gene Ontology Categories:

Process(es)

establishment of mitotic spindle orientation
cell morphogenesis
intracellular protein transport
actin filament organization
negative regulation of microtubule depolymerization
mitotic nuclear division
positive regulation of interleukin-6 production
positive regulation of tumor necrosis factor production
regulation of Rho protein signal transduction
intracellular signal transduction
regulation of cell proliferation
positive regulation of apoptotic process
positive regulation of GTPase activity
innate immune response
positive regulation of transcription from RNA polymerase II promoter
positive regulation of peptidyl-tyrosine phosphorylation
negative regulation of neurogenesis
regulation of small GTPase mediated signal transduction
positive regulation of NF-kappaB transcription factor activity
cell division
negative regulation of necroptotic process
cellular response to muramyl dipeptide
cellular response to tumor necrosis factor
cellular hyperosmotic response
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress

Function(s)

guanyl-nucleotide exchange factor activity
Rho guanyl-nucleotide exchange factor activity
protein binding
microtubule binding
transcription factor binding
zinc ion binding
Rho GTPase binding
Rac guanyl-nucleotide exchange factor activity
Rac GTPase binding