119231

• Gene Symbol: ARHGEF2
• Gene Name: Rho/Rac guanine nucleotide exchange factor 2
• Gene Aliases: GEF, GEF-H1, GEFH1, LFP40, P40
• Chromosome Location: Chr.1: 155946839 - 155991263 on Build GRCh38
• UniGene ID: Hs.743352
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: ARHGEF2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001162383.1	NP_001155855.1	7	831
	NM_001162384.1	NP_001155856.1	7	828
	NM_004723.3	NP_004714.2	7	756
	XM_005245587.2	XP_005245644.1	7	884
	XM_005245588.2	XP_005245645.1	7	881
	XM_005245589.4	XP_005245646.1	7	1037
	XM_005245590.3	XP_005245647.1	7	759
	XM_005245591.3	XP_005245648.1	8	875
	XM_005245592.2	XP_005245649.1	7	1028
	XM_005245593.4	XP_005245650.1	7	759
	XM_005245594.2	XP_005245651.1	7	1745
	XM_006711622.3	XP_006711685.1	7	2022
	XM_006711623.3	XP_006711686.1	6	758
	XM_006711624.3	XP_006711687.1	6	785
	XM_006711625.3	XP_006711688.1	6	691
	XM_006711626.2	XP_006711689.1	6	1677
	XM_011510136.2	XP_011508438.2	11	1440
	XM_011510137.2	XP_011508439.2	11	1443
	XM_011510139.2	XP_011508441.1	11	1443
	XM_011510141.2	XP_011508443.1	7	1561
	XM_011510143.2	XP_011508445.1	3	307
	XM_017002794.1	XP_016858283.1	11	1440
	XM_017002795.1	XP_016858284.1	7	775
	XM_017002796.1	XP_016858285.1	7	2019
	XM_017002797.1	XP_016858286.1	7	759
	XM_017002798.1	XP_016858287.1	6	1954
	XM_017002799.1	XP_016858288.1	6	755
GenBank mRNA	AB014551.3	-	11	1099
	AF486838.1	-	7	710
	AK295924.1	-	7	1028
	AK304548.1	-	10	1168
	AL512715.1	-	7	741
	BC020567.1	-	7	813	4157775
	BT007407.1	-	6	632

More Information

Gene Ontology Categories:

Process(es)

establishment of mitotic spindle orientation
cell morphogenesis
intracellular protein transport
actin filament organization
negative regulation of microtubule depolymerization
mitotic nuclear division
positive regulation of interleukin-6 production
positive regulation of tumor necrosis factor production
regulation of Rho protein signal transduction
intracellular signal transduction
regulation of cell proliferation
positive regulation of apoptotic process
positive regulation of GTPase activity
innate immune response
positive regulation of transcription from RNA polymerase II promoter
positive regulation of peptidyl-tyrosine phosphorylation
negative regulation of neurogenesis
regulation of small GTPase mediated signal transduction
positive regulation of NF-kappaB transcription factor activity
cell division
negative regulation of necroptotic process
cellular response to muramyl dipeptide
cellular response to tumor necrosis factor
cellular hyperosmotic response
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress

Function(s)

guanyl-nucleotide exchange factor activity
Rho guanyl-nucleotide exchange factor activity
protein binding
microtubule binding
transcription factor binding
zinc ion binding
Rho GTPase binding
Rac guanyl-nucleotide exchange factor activity
Rac GTPase binding