119311 Validated

• Gene Symbol: ARHGEF12
• Gene Name: Rho guanine nucleotide exchange factor 12
• Gene Aliases: LARG, PRO2792
• Chromosome Location: Chr.11: 120336276 - 120489936 on Build GRCh38
• UniGene ID: Hs.24598
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: ARHGEF12
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001198665.1	NP_001185594.1	3	418
	NM_001301084.1	NP_001288013.1	3	244
	NM_015313.2	NP_056128.1	3	418
	XM_006718805.3	XP_006718868.1	3	777
	XM_011542720.2	XP_011541022.1	3	359
	XM_017017420.1	XP_016872909.1	3	1051
	XM_017017421.1	XP_016872910.1	3	634
	XM_017017422.1	XP_016872911.1	3	246
GenBank mRNA	AF180681.1	-	3	90
	AK294803.1	-	3	219
	AK304316.1	-	4	699
	AL137456.1	-	2	237
	BC063117.1	-	3	421
	BX647785.1	-	3	220
	BX648515.1	-	3	225
	DC350360.1	-	3	244

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001013246, AY935257.
This siRNA also targets the following transcripts in Mouse: NM_027144, AK009331, AF467766, AK122267, BC052785.

Matching Taqman Gene Expression Assay:

Hs00209661_m1

Panther Classification:

Molecular Function -

guanyl-nucleotide exchange factor

Gene Ontology Categories:

Process(es)

G-protein coupled receptor signaling pathway
regulation of Rho protein signal transduction
intracellular signal transduction
positive regulation of apoptotic process
positive regulation of GTPase activity
regulation of small GTPase mediated signal transduction

Function(s)

G-protein coupled receptor binding
guanyl-nucleotide exchange factor activity
Rho guanyl-nucleotide exchange factor activity
GTPase activator activity
protein binding