12833 Validated

• Gene Symbol: TDG
• Gene Name: thymine DNA glycosylase
• Gene Aliases: hTDG
• Chromosome Location: Chr.12: 103965815 - 103988878 on Build GRCh38
• UniGene ID: Hs.584809
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: TDG
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_003211.4	NP_003202.3	3	409
	XM_005269125.1	XP_005269182.1	3	269
	XM_011538714.1	XP_011537016.1	2	239
	XM_011538715.1	XP_011537017.1	2	239
GenBank mRNA	AK299832.1	-	3	321
	AK303631.1	-	2	236
	AK311673.1	-	2	239
	AK313234.1	-	3	352
	AL710869.1	-	4	561
	BC019925.1	-	3	363
	BC037557.1	-	3	362	5184772
	BC104477.1	-	3	325
	CB047650.1	-	2	220
	DB162106.1	-	3	410

More Information

Matching Taqman Gene Expression Assay:

Hs00702322_s1

Panther Classification:

Molecular Function -

DNA metabolism protein, DNA glycosylase, nucleic acid metabolism protein

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
base-excision repair
base-excision repair, AP site formation
mismatch repair
transcription, DNA-templated
embryo development
covalent chromatin modification
protein sumoylation
negative regulation of protein binding
oxidative DNA demethylation
negative regulation of chromatin binding
regulation of gene expression, epigenetic
depyrimidination
DNA demethylation

Function(s)

RNA polymerase II transcription cofactor activity
damaged DNA binding
double-stranded DNA binding
uracil DNA N-glycosylase activity
protein kinase C binding
protein binding
pyrimidine-specific mismatch base pair DNA N-glycosylase activity
DNA N-glycosylase activity
mismatched DNA binding
SUMO binding
protein homodimerization activity
structure-specific DNA binding