134223

• Gene Symbol: DDX58
• Gene Name: DEXD/H-box helicase 58
• Gene Aliases: RIG-I, RIGI, RLR-1, SGMRT2
• Chromosome Location: Chr.9: 32455302 - 32526324 on Build GRCh38
• UniGene ID: Hs.190622
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: DDX58
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_014314.3	NP_055129.2	12	1895
GenBank mRNA	AK023661.1	-	5	570
	AK125989.1	-	13	2100
	AK301678.1	-	11	1618
	AK315040.1	-	12	1766
	AL137608.1	-	2	156
	BC132786.1	-	12	1843	40146808
	BC136610.1	-	12	1843	9020600
	BX647917.1	-	11	1632

More Information

Gene Ontology Categories:

Process(es)

positive regulation of defense response to virus by host
detection of virus
response to virus
positive regulation of gene expression
regulation of cell migration
negative regulation of type I interferon production
positive regulation of granulocyte macrophage colony-stimulating factor production
positive regulation of interferon-alpha production
positive regulation of interferon-beta production
positive regulation of interleukin-6 production
positive regulation of interleukin-8 production
regulation of type III interferon production
cytoplasmic pattern recognition receptor signaling pathway in response to virus
RIG-I signaling pathway
positive regulation of transcription factor import into nucleus
response to exogenous dsRNA
innate immune response
positive regulation of transcription from RNA polymerase II promoter
positive regulation of sequence-specific DNA binding transcription factor activity

Function(s)

double-stranded DNA binding
double-stranded RNA binding
single-stranded RNA binding
helicase activity
protein binding
ATP binding
zinc ion binding
identical protein binding