134854

• Gene Symbol: SUFU
• Gene Name: SUFU negative regulator of hedgehog signaling
• Gene Aliases: PRO1280, SUFUH, SUFUXL
• Chromosome Location: Chr.10: 102502879 - 102633458 on Build GRCh38
• UniGene ID: Hs.404089
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: SUFU
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_016169.3	NP_057253.2	12	2086
	XM_011539858.2	XP_011538160.1	13	2215
	XM_011539860.2	XP_011538162.1	13	2212
	XM_011539861.2	XP_011538163.1	12	2089
	XM_011539863.2	XP_011538165.1	13	1950
	XM_017016323.1	XP_016871812.1	13	2445
GenBank mRNA	AF159447.1	-	12	2041
	AF172319.1	-	12	1891
	AF175770.1	-	12	2060
	AL137465.1	-	2	574
	BC013291.2	-	12	2062	3533158

More Information

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
skeletal system development
neural tube closure
heart looping
ventricular septum development
regulation of transcription, DNA-templated
proteolysis
signal transduction
multicellular organism development
smoothened signaling pathway involved in ventral spinal cord interneuron specification
smoothened signaling pathway involved in spinal cord motor neuron cell fate specification
aorta development
negative regulation of transcription factor import into nucleus
cytoplasmic sequestering of transcription factor
negative regulation of sequence-specific DNA binding transcription factor activity
skin development
negative regulation of osteoblast differentiation
negative regulation of smoothened signaling pathway
coronary vasculature development
negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Function(s)

transcription corepressor activity
signal transducer activity
protein binding
beta-catenin binding
transcription factor binding
protein kinase binding