13535 Validated

• Gene Symbol: AKR1C3
• Gene Name: aldo-keto reductase family 1, member C3
• Gene Aliases: DD3, DDX, HA1753, HAKRB, HAKRe, HSD17B5, PGFS, hluPGFS
• Chromosome Location: Chr.10: 5048766 - 5107686 on Build GRCh38
• UniGene ID: Hs.78183
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: AKR1C3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001253908.1	NP_001240837.1	1, 2	138
	NM_001253909.1	NP_001240838.1	1, 2	161
	NM_003739.5	NP_003730.4	1, 2	161
GenBank mRNA	AB018580.1	-	1, 2	139
	AF149416.2	-	1, 2	103
	AK290365.1	-	1, 2	121
	AK296701.1	-	1, 2	123
	AK310940.1	-	1, 2	119
	AK315411.1	-	1, 2	121
	AV761799.2	-	1, 2	163
	BC019230.1	-	1, 2	118	3682448
	BG547635.1	-	1, 2	162
	D17793.1	-	1, 2	143
	S68288.1	-	1, 2	102

More Information

Matching Taqman Gene Expression Assay:

Hs00366267_m1

Panther Classification:

Molecular Function -

oxidoreductase, reductase, metabolite interconversion enzyme

Gene Ontology Categories:

Process(es)

protein import into nucleus, translocation
retinoid metabolic process
prostaglandin metabolic process
G-protein coupled receptor signaling pathway
response to nutrient
steroid metabolic process
positive regulation of cell proliferation
male gonad development
cellular response to starvation
positive regulation of cell death
farnesol catabolic process
cyclooxygenase pathway
keratinocyte differentiation
cellular response to reactive oxygen species
progesterone metabolic process
retinol metabolic process
retinal metabolic process
multicellular organismal macromolecule metabolic process
daunorubicin metabolic process
doxorubicin metabolic process
regulation of retinoic acid receptor signaling pathway
positive regulation of protein kinase B signaling
oxidation-reduction process
testosterone biosynthetic process
renal absorption
cellular response to cadmium ion
cellular response to calcium ion
cellular response to prostaglandin stimulus
cellular response to corticosteroid stimulus
cellular response to jasmonic acid stimulus
cellular response to prostaglandin D stimulus
negative regulation of retinoic acid biosynthetic process
regulation of testosterone biosynthetic process
positive regulation of endothelial cell apoptotic process
positive regulation of reactive oxygen species metabolic process

Function(s)

retinal dehydrogenase activity
alditol:NADP+ 1-oxidoreductase activity
aldo-keto reductase (NADP) activity
retinol dehydrogenase activity
oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
phenanthrene 9,10-monooxygenase activity
dihydrotestosterone 17-beta-dehydrogenase activity
prostaglandin H2 endoperoxidase reductase activity
prostaglandin D2 11-ketoreductase activity
geranylgeranyl reductase activity
ketoreductase activity
prostaglandin-F synthase activity
15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity
androsterone dehydrogenase activity
testosterone dehydrogenase (NAD+) activity
testosterone 17-beta-dehydrogenase (NADP+) activity
ketosteroid monooxygenase activity
trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity
indanol dehydrogenase activity
delta4-3-oxosteroid 5beta-reductase activity
NADP-retinol dehydrogenase activity