138749

• Gene Symbol: GDF5
• Gene Name: growth differentiation factor 5
• Gene Aliases: BDA1C, BMP-14, BMP14, CDMP1, LAP-4, LAP4, OS5, SYM1B, SYNS2
• Chromosome Location: Chr.20: 35433347 - 35454746 on Build GRCh38
• UniGene ID: Hs.1573
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: GDF5
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000557.4	NP_000548.2	2	1362
	NM_001319138.1	NP_001306067.1	4	1604
	XM_011529075.2	XP_011527377.1	4	1494
GenBank mRNA	AB593125.1	-	2	1350
	BC032495.1	-	4	1604	5243109
	BC111566.1	-	1	269
	BC111859.1	-	1	269
	U13660.1	-	2	1362

More Information

Panther Classification:

Molecular Function -

growth factor

Gene Ontology Categories:

Process(es)

chondrocyte differentiation
transforming growth factor beta receptor signaling pathway
SMAD protein import into nucleus
cell-cell signaling
positive regulation of pathway-restricted SMAD protein phosphorylation
embryonic limb morphogenesis
positive regulation of BMP signaling pathway
negative regulation of chondrocyte differentiation
positive regulation of chondrocyte differentiation
forelimb morphogenesis
hindlimb morphogenesis
growth
regulation of multicellular organism growth
regulation of apoptotic process
regulation of MAPK cascade
negative regulation of neuron apoptotic process
positive regulation of neuron differentiation
cell development
negative regulation of epithelial cell proliferation
SMAD protein signal transduction
chondroblast differentiation
mitophagy in response to mitochondrial depolarization
negative regulation of mesenchymal cell apoptotic process

Function(s)

cytokine activity
transforming growth factor beta receptor binding
protein binding
growth factor activity
BMP binding
identical protein binding