139535

• Gene Symbol: TERF2
• Gene Name: telomeric repeat binding factor 2
• Gene Aliases: TRBF2, TRF2
• Chromosome Location: Chr.16: 69355561 - 69386004 on Build GRCh38
• UniGene ID: Hs.63335
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: TERF2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_005652.4	NP_005643.2	3	593
	XM_005256121.3	XP_005256178.1	3	609
	XM_005256122.3	XP_005256179.1	3	609
	XM_005256123.3	XP_005256180.1	3	609
	XM_005256124.3	XP_005256181.1	3	609
GenBank mRNA	AF002999.1	-	3	574
	BC024890.1	-	3	576	4346819
	U95970.1	-	3	332

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: XM_003752261, XM_003752235, XM_003752281, XM_003752247, XM_008773769, and others.

Gene Ontology Categories:

Process(es)

telomere maintenance
telomere maintenance via telomerase
cell cycle
positive regulation of gene expression
negative regulation of gene expression
telomere capping
telomeric loop formation
protection from non-homologous end joining at telomere
regulation of telomere maintenance
negative regulation of telomere maintenance
positive regulation of telomere maintenance
negative regulation of telomere maintenance via recombination
regulation of telomere maintenance via telomerase
negative regulation of telomere maintenance via semi-conservative replication
positive regulation of nitric-oxide synthase activity
protein localization to chromosome, telomeric region
cellular senescence
negative regulation of beta-galactosidase activity
negative regulation of telomere single strand break repair
negative regulation of telomere capping
negative regulation of t-circle formation
negative regulation of cellular senescence

Function(s)

double-stranded telomeric DNA binding
telomerase activity
protein binding
protein C-terminus binding
telomeric DNA binding
protein homodimerization activity
macromolecular complex binding
G-rich strand telomeric DNA binding