139855

Gene Symbol:

KDM6A UTY

Gene Name:

lysine demethylase 6A

ubiquitously transcribed tetratricopeptide repeat containing, Y-linked

Gene Aliases:

KABUK2, UTX, bA386N14.2

KDM6AL, UTY1

Chromosome Location:

Chr.X: 44873175 - 45112612 on Build GRCh38

Chromosome Location:

Chr.Y: 13230770 - 13480670 on Build GRCh38

UniGene ID:

Hs.522616

Hs.115277

Species:

Human

Species Specific ID (Flybase ID):

-

-

siRNA Details

Gene Symbol: KDM6A
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001291415.1	NP_001278344.1	12, 13	1579
	NM_021140.3	NP_066963.2	12, 13	1579
	XM_005272656.4	XP_005272713.1	12, 13	1579
	XM_005272659.4	XP_005272716.1	12, 13	1579
	XM_011543957.2	XP_011542259.1	13, 14	1636
	XM_011543958.2	XP_011542260.1	12, 13	1579
	XM_011543959.2	XP_011542261.1	13, 14	1636
	XM_011543960.2	XP_011542262.1	13, 14	1636
	XM_011543962.2	XP_011542264.1	13, 14	1636
	XM_011543964.2	XP_011542266.1	12, 13	1579
	XM_011543966.2	XP_011542268.1	13, 14	1636
	XM_011543967.2	XP_011542269.1	13, 14	1636
	XM_011543970.2	XP_011542272.1	12, 13	1579
	XM_011543974.1	XP_011542276.1	12, 13	1579
	XM_011543975.2	XP_011542277.1	8, 9	749
GenBank mRNA	AB208795.1	-	12, 13	1532
	AF000992.1	-	12, 13	1228
	AF000993.1	-	12, 13	1228
	AK304114.1	-	12, 13	1615
	AK307691.1	-	2, 3	314
	BC093868.1	-	12, 13	1225	7939713
	BC113381.1	-	12, 13	1225	8322433
	BC143277.1	-	12, 13	1225	9051779

Gene Symbol: UTY
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001258249.1	NP_001245178.1	12, 13	2198
	NM_001258252.1	NP_001245181.1	12, 13	2198
	NM_001258254.1	NP_001245183.1	12, 13	2198
	NM_001258255.1	NP_001245184.1	12, 13	2198
	NM_001258256.1	NP_001245185.1	12, 13	2198
	NM_001258261.1	NP_001245190.1	11, 12	2099
	NM_001258262.1	NP_001245191.1	12, 13	2198
	NM_001258264.1	NP_001245193.1	12, 13	2150
	NM_001258266.1	NP_001245195.1	12, 13	2198
	NM_001258268.1	NP_001245197.1	12, 13	2198
	NM_001258269.1	NP_001245198.1	12, 13	2198
	NR_047598.1		13, 14	2299
	NR_047600.1		11, 12	2163
	NR_047601.1		12, 13	2198
	NR_047607.1		12, 13	2198
	NR_047608.1		12, 13	2150
	NR_047611.1		12, 13	2198
	NR_047612.1		12, 13	2198
	NR_047613.1		11, 12	2148
	NR_047618.1		12, 13	2198
	NR_047620.1		12, 13	2198
	NR_047621.1		12, 13	2269
	NR_047622.1		11, 12	2099
	NR_047623.1		12, 13	2198
	NR_047633.1		12, 13	2198
	NR_047643.1		12, 13	2198
	NR_047644.1		12, 13	2198
	NR_047645.1		12, 13	2269
	XM_005262518.3	XP_005262575.1	12, 13	1544
	XM_006724875.3	XP_006724938.1	12, 13	1544
	XM_011531441.2	XP_011529743.1	12, 13	1544
	XM_011531442.2	XP_011529744.1	12, 13	1544
	XM_011531443.2	XP_011529745.1	12, 13	1544
	XM_011531446.2	XP_011529748.1	12, 13	1544
	XM_011531449.2	XP_011529751.1	12, 13	1544
	XM_011531453.2	XP_011529755.1	12, 13	1544
	XM_011531454.2	XP_011529756.1	12, 13	1544
	XM_011531455.2	XP_011529757.1	12, 13	1544
	XM_011531457.2	XP_011529759.1	12, 13	1544
	XM_011531458.2	XP_011529760.1	12, 13	1544
	XM_011531459.2	XP_011529761.1	12, 13	1544
	XM_011531460.2	XP_011529762.1	12, 13	1544
	XM_011531461.2	XP_011529763.1	12, 13	1544
	XM_011531462.2	XP_011529764.1	12, 13	1544
	XM_011531463.2	XP_011529765.1	12, 13	1544
	XM_011531464.2	XP_011529766.1	12, 13	1544
	XM_017030066.1	XP_016885555.1	12, 13	1544
	XM_017030067.1	XP_016885556.1	12, 13	1544
	XM_017030070.1	XP_016885559.1	12, 13	1544
	XM_017030071.1	XP_016885560.1	12, 13	1544
	XM_017030074.1	XP_016885563.1	12, 13	1544
GenBank mRNA	AY769061.1	-	13, 14	1294
	AY769066.1	-	12, 13	1193
	CR936684.1	-	1, 2	29
	DQ140389.1	-	12, 13	1193
	DQ140390.1	-	12, 13	1193
	DQ345542.1	-	11, 12	1158
	DQ345544.1	-	12, 13	1193
	DQ350456.1	-	11, 12	1158
	EF491796.1	-	1, 2	113
	EF612660.1	-	12, 13	1193
	EF612662.1	-	12, 13	1193
	EF612663.1	-	12, 13	1193
	EF612668.1	-	12, 13	1193
	EF612675.1	-	12, 13	1145
	EF612677.1	-	12, 13	1193
	EF612679.1	-	12, 13	1193
	EF612683.1	-	11, 12	1094
	EF612684.1	-	12, 13	1193
	EF612685.1	-	12, 13	1193
	EF612686.1	-	12, 13	1193
	EF612689.1	-	12, 13	1193
	EF612691.1	-	12, 13	1193
	EF612695.1	-	12, 13	1145
	EF653168.1	-	12, 13	1193
	EF653175.1	-	13, 14	1299
	EF653177.1	-	12, 13	1193
	EF653200.1	-	12, 13	1193
	EF653207.1	-	12, 13	1193
	EF653216.1	-	11, 12	1110
	EF653219.1	-	12, 13	1193
	EF653220.1	-	12, 13	1193
	EF653222.1	-	13, 14	1273
	EF653224.1	-	12, 13	1193
	EF685285.1	-	12, 13	1145
	EF685286.1	-	12, 13	1193
	EF685288.1	-	12, 13	1193
	EF685290.1	-	11, 12	1143
	EF685295.1	-	12, 13	1193
	EF685297.1	-	12, 13	1193
	EF685298.1	-	12, 13	1264
	EF685300.1	-	11, 12	1094
	EF685301.1	-	12, 13	1193
	EF685306.1	-	11, 12	1094
	EF685330.1	-	11, 12	1094
	EU026280.1	-	12, 13	1216
	EU026290.1	-	10, 11	1103
	EU026292.1	-	12, 13	1193
	EU026302.1	-	13, 14	1322
	EU026303.1	-	12, 13	1188
	EU026309.1	-	12, 13	1145
	EU026311.1	-	12, 13	1193
	EU026314.1	-	13, 14	1299
	EU026317.1	-	12, 13	1193
	EU026320.1	-	13, 14	1299
	EU026321.1	-	12, 13	1188
	EU026323.1	-	11, 12	1153
	EU026325.1	-	12, 13	1193
	EU026335.1	-	12, 13	1193
	EU026342.1	-	10, 11	1108
	EU116343.1	-	6, 7	586
	EU116347.1	-	10, 11	1064

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: XM_008773698, XM_008773696, XM_008773047, XM_008773695, XM_008773697, and others.
This siRNA also targets the following transcripts in Mouse: NM_009483, NM_009484, AK080370, AF057367, AK142512, and others.

Panther Classification:

Molecular Function -

chromatin/chromatin-binding, or -regulatory protein

Gene Ontology Categories:

Process(es)

in utero embryonic development
neural tube closure
heart morphogenesis
respiratory system process
positive regulation of gene expression
somite rostral/caudal axis specification
multicellular organism growth
mesodermal cell differentiation
notochord morphogenesis
histone H3-K4 methylation
oxidation-reduction process
canonical Wnt signaling pathway
histone H3-K27 demethylation
regulation of gene expression

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
chromatin DNA binding
histone demethylase activity
identical protein binding
metal ion binding
dioxygenase activity
histone demethylase activity (H3-K27 specific)