14084

• Gene Symbol: DLG1
• Gene Name: discs large MAGUK scaffold protein 1
• Gene Aliases: DLGH1, SAP-97, SAP97, dJ1061C18.1.1, hdlg
• Chromosome Location: Chr.3: 197042560 - 197299272 on Build GRCh38
• UniGene ID: Hs.292549
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: DLG1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001098424.1	NP_001091894.1	5	524
	NM_001204386.1	NP_001191315.1	5	524
	NM_001290983.1	NP_001277912.1	5	593
	NM_004087.2	NP_004078.2	5	524
	XM_005269289.3	XP_005269346.1	5	806
	XM_011512502.2	XP_011510804.1	5	806
	XM_011512503.1	XP_011510805.1	5	803
	XM_011512505.1	XP_011510807.1	5	803
	XM_011512506.1	XP_011510808.1	5	803
	XM_011512509.1	XP_011510811.1	5	803
	XM_017005800.1	XP_016861289.1	5	941
	XM_017005801.1	XP_016861290.1	5	461
	XM_017005802.1	XP_016861291.1	5	531
	XM_017005803.1	XP_016861292.1	5	452
	XM_017005804.1	XP_016861293.1	5	806
	XM_017005805.1	XP_016861294.1	5	623
	XM_017005806.1	XP_016861295.1	5	803
	XM_017005807.1	XP_016861296.1	5	902
	XM_017005808.1	XP_016861297.1	5	461
	XM_017005809.1	XP_016861298.1	5	563
	XM_017005810.1	XP_016861299.1	5	461
	XM_017005811.1	XP_016861300.1	5	803
	XM_017005812.1	XP_016861301.1	5	457
	XM_017005813.1	XP_016861302.1	5	461
	XM_017005814.1	XP_016861303.1	5	564
	XM_017005815.1	XP_016861304.1	5	803
	XM_017005816.1	XP_016861305.1	5	902
	XM_017005817.1	XP_016861306.1	5	433
	XM_017005818.1	XP_016861307.1	5	535
	XM_017005819.1	XP_016861308.1	5	452
	XM_017005820.1	XP_016861309.1	5	521
GenBank mRNA	AK293967.1	-	2	181
	AK304280.1	-	5	524
	AK310596.1	-	5	462
	AK310893.1	-	5	808
	BC015560.2	-	5	763
	BC028486.1	-	5	763
	BC140841.1	-	5	489	9021709
	BC144651.1	-	5	489	9053182
	EF553524.1	-	5	593
	U13896.1	-	5	522
	U13897.1	-	5	522

More Information

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
branching involved in ureteric bud morphogenesis
immunological synapse formation
endothelial cell proliferation
lens development in camera-type eye
T cell cytokine production
protein dephosphorylation
actin filament organization
mitotic cell cycle checkpoint
establishment or maintenance of cell polarity
chemical synaptic transmission
nervous system development
positive regulation of cell proliferation
regulation of cell shape
viral process
single organismal cell-cell adhesion
peristalsis
positive regulation of actin filament polymerization
cortical actin cytoskeleton organization
astral microtubule organization
membrane raft organization
regulation of myelination
activation of protein kinase activity
ion transmembrane transport
cellular protein complex localization
T cell activation
negative regulation of T cell proliferation
regulation of membrane potential
amyloid precursor protein metabolic process
receptor clustering
positive regulation of potassium ion transport
cortical microtubule organization
establishment or maintenance of epithelial cell apical/basal polarity
negative regulation of mitotic cell cycle
GMP metabolic process
GDP metabolic process
reproductive structure development
embryonic skeletal system morphogenesis
smooth muscle tissue development
negative regulation of epithelial cell proliferation
establishment of centrosome localization
negative regulation of protein kinase B signaling
hard palate development
negative regulation of ERK1 and ERK2 cascade
bicellular tight junction assembly
protein localization to plasma membrane
positive regulation of establishment of protein localization to plasma membrane
receptor localization to synapse
regulation of NIK/NF-kappaB signaling
regulation of sodium ion transmembrane transport
negative regulation of p38MAPK cascade

Function(s)

guanylate kinase activity
phosphoprotein phosphatase activity
protein binding
protein C-terminus binding
cytoskeletal protein binding
ligand-gated ion channel activity
potassium channel regulator activity
protein kinase binding
phosphatase binding
mitogen-activated protein kinase kinase binding
protein complex scaffold
ionotropic glutamate receptor binding
ion channel binding
L27 domain binding
cadherin binding involved in cell-cell adhesion