142094

• Gene Symbol: PSEN2
• Gene Name: presenilin 2
• Gene Aliases: AD3L, AD4, CMD1V, PS2, STM2
• Chromosome Location: Chr.1: 226870572 - 226903829 on Build GRCh38
• UniGene ID: Hs.25363
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: PSEN2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000447.2	NP_000438.2	5	674
	NM_012486.2	NP_036618.2	5	674
	XM_005273199.3	XP_005273256.1	4	487
	XM_017001835.1	XP_016857324.1	4	995
	XM_017001836.1	XP_016857325.1	4	487
GenBank mRNA	AF416718.1	-	3	315
	AK292299.1	-	6	626
	AK301143.1	-	4	423
	BC006365.2	-	6	868	4131408
	BT006984.1	-	3	247
	DA915823.1	-	5	627
	L43964.1	-	4	614
	L44577.1	-	5	612
	U34349.1	-	3	338

More Information

Panther Classification:

Molecular Function -

aspartic protease

Gene Ontology Categories:

Process(es)

response to hypoxia
membrane protein ectodomain proteolysis
calcium ion transport
Notch signaling pathway
Notch receptor processing
protein processing
membrane protein intracellular domain proteolysis
intracellular signal transduction
amyloid precursor protein catabolic process
positive regulation of apoptotic process
negative regulation of apoptotic process
positive regulation of catalytic activity
ephrin receptor signaling pathway
beta-amyloid metabolic process

Function(s)

endopeptidase activity
aspartic-type endopeptidase activity
protein binding