143233

• Gene Symbol: CIITA
• Gene Name: class II, major histocompatibility complex, transactivator
• Gene Aliases: C2TA, CIITAIV, MHC2TA, NLRA
• Chromosome Location: Chr.16: 10866208 - 10941562 on Build GRCh38
• UniGene ID: Hs.592051
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: CIITA
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000246.3	NP_000237.2	2	249
	NM_001286402.1	NP_001273331.1	2	249
	NM_001286403.1	NP_001273332.1	2	249
	NR_104444.1		2	249
	XM_006720880.3	XP_006720943.2	2	427
	XM_011522484.2	XP_011520786.1	2	427
	XM_011522485.2	XP_011520787.1	2	427
	XM_011522486.2	XP_011520788.1	2	429
	XM_011522487.2	XP_011520789.1	2	311
	XM_011522488.2	XP_011520790.1	2	1658
	XM_011522489.2	XP_011520791.1	2	311
	XM_011522490.2	XP_011520792.1	2	1659
	XM_011522491.2	XP_011520793.1	2	429
	XM_011522492.2	XP_011520794.1	2	375
	XM_011522493.2	XP_011520795.1	2	375
	XM_011522494.2	XP_011520796.1	2	139
	XM_011522495.2	XP_011520797.1	2	377
	XM_011522496.2	XP_011520798.1	2	377
GenBank mRNA	AF410154.1	-	2	254
	AY084054.1	-	2	239
	AY084055.1	-	2	239
	BE247223.1	-	2	250
	U18259.1	-	2	254
	U18288.1	-	2	231
	U31931.1	-	2	116
	X74301.1	-	2	231

More Information

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
immune response
phosphorylation
negative regulation of collagen biosynthetic process
response to interferon-gamma
positive regulation of MHC class I biosynthetic process
positive regulation of MHC class II biosynthetic process
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
response to antibiotic
interferon-gamma-mediated signaling pathway

Function(s)

DNA binding
transcription coactivator activity
protein binding
ATP binding
GTP binding
protein C-terminus binding
kinase activity
transferase activity, transferring acyl groups
protein complex binding
activating transcription factor binding
transcription regulatory region DNA binding