143706

Gene Symbol:

PAK2 LOC646214

Gene Name:

p21 (RAC1) activated kinase 2

p21 protein (Cdc42/Rac)-activated kinase 2 pseudogene

Gene Aliases:

PAK65, PAKgamma

-

Chromosome Location:

Chr.3: 196739857 - 196832647 on Build GRCh38

Chromosome Location:

Chr.15: 21289604 - 21297829 on Build GRCh38

UniGene ID:

Hs.518530

Hs.510697

Species:

Human

Species Specific ID (Flybase ID):

-

-

siRNA Details

Gene Symbol: PAK2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_002577.4	NP_002568.2	2	417
	XM_011512870.2	XP_011511172.1	2	140
	XM_017006501.1	XP_016861990.1	3	604
GenBank mRNA	AK291339.1	-	2	301
	BC069613.1	-	1	130	7262289
	U24153.1	-	1	134

Gene Symbol: LOC646214
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NR_027053.2		1	2708
GenBank mRNA	AB209428.1	-	1	2728

More Information

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

mitotic cell cycle
stimulatory C-type lectin receptor signaling pathway
protein phosphorylation
negative regulation of protein kinase activity
apoptotic process
signal transduction
viral process
phosphorylation
peptidyl-serine phosphorylation
signal transduction by protein phosphorylation
T cell costimulation
Fc-epsilon receptor signaling pathway
regulation of growth
negative regulation of apoptotic process
protein autophosphorylation
vascular endothelial growth factor receptor signaling pathway
regulation of defense response to virus by virus
positive regulation of peptidyl-tyrosine phosphorylation
T cell receptor signaling pathway
dendritic spine development
positive regulation of protein tyrosine kinase activity
cellular response to organic cyclic compound
cell-cell adhesion
positive regulation of extrinsic apoptotic signaling pathway
negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis

Function(s)

protein kinase activity
protein serine/threonine kinase activity
receptor signaling protein serine/threonine kinase activity
protein binding
ATP binding
protein kinase binding
protein tyrosine kinase activator activity
identical protein binding
cadherin binding involved in cell-cell adhesion