145244

• Gene Symbol: UBE2K
• Gene Name: ubiquitin conjugating enzyme E2 K
• Gene Aliases: E2-25K, HIP2, HYPG, LIG, UBC1
• Chromosome Location: Chr.4: 39698044 - 39782792 on Build GRCh38
• UniGene ID: Hs.50308
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: UBE2K
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001111112.1	NP_001104582.1	3, 4	508
	NM_001312647.1	NP_001299576.1	3, 4	420
	NM_001312648.1	NP_001299577.1	2, 3	414
	NM_005339.4	NP_005330.1	3, 4	508
GenBank mRNA	AB022435.1	-	3, 4	310
	AK093533.1	-	3, 4	329
	AK307130.1	-	2, 3	319
	AK315524.1	-	3, 4	434
	BC022804.1	-	3, 4	384	4893778
	BC050600.1	-	3, 4	362	6502901
	CX786829.1	-	3, 4	347
	DA526283.1	-	3, 4	508
	U58522.1	-	3, 4	227

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001106006, XM_006250934, FQ233155, FQ234076, FQ226880.
This siRNA also targets the following transcripts in Mouse: NM_016786, AK048194, AK036068, BC002013, AK018366, and others.

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

ubiquitin-dependent protein catabolic process
positive regulation of peptidyl-threonine phosphorylation
free ubiquitin chain polymerization
regulation of proteasomal ubiquitin-dependent protein catabolic process
cellular response to interferon-beta
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of type I interferon-mediated signaling pathway
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
protein K48-linked ubiquitination

Function(s)

ubiquitin-protein transferase activity
protein binding
ATP binding
ubiquitin protein ligase binding
ubiquitin-ubiquitin ligase activity