145810

• Gene Symbol: DKC1
• Gene Name: dyskerin pseudouridine synthase 1
• Gene Aliases: CBF5, DKC, DKCX, NAP57, NOLA4, XAP101
• Chromosome Location: Chr.X: 154762742 - 154777689 on Build GRCh38
• UniGene ID: Hs.4747
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: DKC1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001142463.2	NP_001135935.1	6, 7	736
	NM_001288747.1	NP_001275676.1	6, 7	736
	NM_001363.4	NP_001354.1	6, 7	736
	NR_110021.1		5, 6	1213
	NR_110022.1		5, 6	1332
	NR_110023.1		6, 7	736
GenBank mRNA	AF067008.1	-	6, 7	572
	AK225077.1	-	6, 7	600
	AK307672.1	-	6, 7	625
	BC009928.2	-	6, 7	714	3604732
	BC010015.2	-	6, 7	538	4303933
	JF279874.1	-	6, 7	559
	KC954523.1	-	5, 6	1036
	KC954524.1	-	5, 6	1155
	KC954525.1	-	6, 7	559
	U59151.1	-	6, 7	592

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_001030307, BC068171, BC099966, AK144139, AK166105, and others.

Panther Classification:

Molecular Function -

centromere DNA-binding protein

Gene Ontology Categories:

Process(es)

box H/ACA snoRNA 3'-end processing
rRNA processing
RNA processing
telomere maintenance via telomerase
cell proliferation
rRNA pseudouridine synthesis
snRNA pseudouridine synthesis
positive regulation of telomere maintenance via telomerase
positive regulation of telomerase activity
telomerase RNA stabilization
positive regulation of establishment of protein localization to telomere
positive regulation of telomerase RNA localization to Cajal body
mRNA pseudouridine synthesis

Function(s)

telomerase activity
RNA binding
protein binding
pseudouridine synthase activity
box H/ACA snoRNA binding
poly(A) RNA binding
telomerase RNA binding