150107

• Gene Symbol: Pik3ca
• Gene Name: phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
• Gene Aliases: 6330412C24Rik, caPI3K, p110, p110alpha
• Chromosome Location: Chr.3: 32397055 - 32468486 on Build GRCm38
• UniGene ID: Mm.260521
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Pik3ca
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_008839.2	NP_032865.2	18	2786
GenBank mRNA	AK051885.1	-	18	2419
	BC089038.1	-	18	2786	30692343
	BC130228.1	-	18	2735	40141870
	U03279.1	-	18	2731

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_133399, XM_008773148, AF395897.

Panther Classification:

Molecular Function -

kinase

Gene Ontology Categories:

Process(es)

angiogenesis
liver development
adaptive immune response
glucose metabolic process
protein phosphorylation
inflammatory response
phosphatidylinositol 3-kinase signaling
phosphorylation
platelet activation
positive regulation of peptidyl-serine phosphorylation
phosphatidylinositol-3-phosphate biosynthetic process
regulation of multicellular organism growth
regulation of cellular respiration
protein kinase B signaling
negative regulation of neuron apoptotic process
hypomethylation of CpG island
innate immune response
positive regulation of protein kinase activity
phosphatidylinositol phosphorylation
phosphatidylinositol-mediated signaling
cell chemotaxis
adipose tissue development
cellular response to glucose stimulus
energy homeostasis
mitophagy in response to mitochondrial depolarization
negative regulation of fibroblast apoptotic process
regulation of genetic imprinting
negative regulation of anoikis

Function(s)

nucleotide binding
protein serine/threonine kinase activity
protein binding
ATP binding
kinase activity
1-phosphatidylinositol-3-kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
phosphotransferase activity, alcohol group as acceptor
protein kinase activator activity
1-phosphatidylinositol-4-phosphate 3-kinase activity
insulin receptor substrate binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity