152193

• Gene Symbol: Plcb1
• Gene Name: phospholipase C, beta 1
• Gene Aliases: 3110043I21Rik, AI132408, Plcb, mKIAA0581
• Chromosome Location: Chr.2: 134786164 - 135475258 on Build GRCm38
• UniGene ID: Mm.330607
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Plcb1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001145830.1	NP_001139302.1	4	677
	NM_019677.2	NP_062651.2	4	677
GenBank mRNA	AF022801.1	-	3	225
	AF498249.1	-	4	308
	AF498250.1	-	4	308
	AK141164.1	-	4	624
	AK141464.1	-	4	613
	AK143153.1	-	4	678
	BC058710.1	-	4	644	6842016
	U85712.1	-	4	311
	U85713.1	-	4	311
	U85714.1	-	4	311

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001077641, XM_008762247, L14323, M20636.

Panther Classification:

Molecular Function -

phospholipase

Gene Ontology Categories:

Process(es)

G2/M transition of mitotic cell cycle
oocyte maturation
mRNA processing
lipid metabolic process
cell adhesion
signal transduction
G-protein coupled acetylcholine receptor signaling pathway
glutamate receptor signaling pathway
brain development
memory
regulation of G-protein coupled receptor protein signaling pathway
insulin receptor signaling pathway
lipid catabolic process
cerebral cortex development
erythrocyte differentiation
macrophage differentiation
positive regulation of sodium:proton antiporter activity
positive regulation of interleukin-12 production
response to monosaccharide
intracellular signal transduction
interleukin-12-mediated signaling pathway
interleukin-15-mediated signaling pathway
positive regulation of embryonic development
response to peptide hormone
positive regulation of GTPase activity
fat cell differentiation
positive regulation of myoblast differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of JNK cascade
insulin-like growth factor receptor signaling pathway
positive regulation of developmental growth
regulation of cell cycle
activation of meiosis involved in egg activation
interleukin-1-mediated signaling pathway
regulation of fertilization
positive regulation of G1/S transition of mitotic cell cycle
positive regulation of acrosome reaction
negative regulation of monocyte extravasation
positive regulation of CD24 biosynthetic process

Function(s)

phosphatidylinositol phospholipase C activity
signal transducer activity
GTPase activator activity
calcium ion binding
protein binding
calmodulin binding
lamin binding
phosphatidylinositol-4,5-bisphosphate binding
phosphoric diester hydrolase activity
hydrolase activity
enzyme binding
protein homodimerization activity