155643

• Gene Symbol: Npc1
• Gene Name: Niemann-Pick type C1
• Gene Aliases: A430089E03Rik, C85354, D18Ertd139e, D18Ertd723e, lcsd, nmf164, spm
• Chromosome Location: Chr.18: 12189694 - 12236386 on Build GRCm38
• UniGene ID: Mm.3484
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Npc1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_008720.2	NP_032746.2	8	1164
GenBank mRNA	AF003348.1	-	8	1141
	AK154282.1	-	8	1084
	AK155379.1	-	8	1084
	AK203292.1	-	2	130
	BC052437.1	-	8	1164	6405214
	BC054539.1	-	8	1164	6405214

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_153624, XM_006254403.

Gene Ontology Categories:

Process(es)

protein glycosylation
lipid metabolic process
endocytosis
autophagy
adult walking behavior
steroid metabolic process
cholesterol metabolic process
negative regulation of macroautophagy
cholesterol transport
membrane raft organization
cholesterol efflux
response to drug
cholesterol homeostasis
response to cadmium ion
viral entry into host cell
negative regulation of cell death
cellular response to steroid hormone stimulus
cellular response to low-density lipoprotein particle stimulus
establishment of protein localization to membrane
positive regulation of cholesterol homeostasis

Function(s)

protein binding
hedgehog receptor activity
cholesterol binding