155769

• Gene Symbol: Pak3
• Gene Name: p21 protein (Cdc42/Rac)-activated kinase 3
• Gene Aliases: PAK-3, Pak65alpha, Pak65beta, Stk4
• Chromosome Location: Chr.X: 143518368 - 143797796 on Build GRCm38
• UniGene ID: Mm.40035
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Pak3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001195046.1	NP_001181975.1	11	1055
	NM_001195047.1	NP_001181976.1	10	1010
	NM_001195048.1	NP_001181977.1	11	1165
	NM_001195049.1	NP_001181978.1	13	1429
	NM_008778.3	NP_032804.2	10	1038
GenBank mRNA	AF082297.1	-	9	952
	AJ496262.1	-	9	920
	AJ496263.1	-	10	965
	AK158893.1	-	11	1165
	AM943853.1	-	10	983
	AM943854.1	-	11	1028
	BC053403.1	-	10	1045	30060082
	U39738.1	-	14	1436

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_019210, XM_006257339, XM_006257338, XM_006257336, XM_008773404, and others.

Gene Ontology Categories:

Process(es)

MAPK cascade
activation of MAPK activity
protein phosphorylation
Rho protein signal transduction
multicellular organism development
regulation of mitotic cell cycle
axonogenesis
metabolic process
regulation of neuron projection development
phosphorylation
dendrite development
cell migration
signal transduction by protein phosphorylation
actin cytoskeleton organization
regulation of actin filament polymerization
stress-activated protein kinase signaling cascade
activation of protein kinase activity
regulation of apoptotic process
regulation of MAPK cascade
positive regulation of neuron apoptotic process
dendritic spine development
positive regulation of dendritic spine morphogenesis
cellular response to organic cyclic compound
positive regulation of DNA biosynthetic process

Function(s)

nucleotide binding
catalytic activity
protein kinase activity
protein serine/threonine kinase activity
MAP kinase kinase activity
protein binding
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
Rho GTPase binding
SH3 domain binding
metal ion binding
Rac GTPase binding
GTPase binding