157593

• Gene Symbol: Fxn
• Gene Name: frataxin
• Gene Aliases: FA, FARR, Frda, X25
• Chromosome Location: Chr.19: 24261453 - 24280586 on Build GRCm38
• UniGene ID: Mm.7319
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Fxn
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_008044.2	NP_032070.1	2, 3	283
GenBank mRNA	AK148147.1	-	2, 3	305
	AK160458.1	-	2, 3	293
	BC016644.1	-	1, 2	996
	BC038010.1	-	1, 2	1007
	BC058533.1	-	2, 3	265
	BC125337.1	-	2, 3	281	40129852
	BC132337.1	-	2, 3	281	40130614
	U95736.1	-	2, 3	283

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001191952, XM_008760308.

Panther Classification:

Molecular Function -

transfer/carrier protein

Gene Ontology Categories:

Process(es)

oxidative phosphorylation
heme biosynthetic process
transport
ion transport
cellular iron ion homeostasis
mitochondrion organization
adult walking behavior
positive regulation of cell proliferation
aerobic respiration
embryo development ending in birth or egg hatching
response to iron ion
regulation of ferrochelatase activity
iron-sulfur cluster assembly
protein autoprocessing
iron incorporation into metallo-sulfur cluster
proprioception
positive regulation of cell growth
negative regulation of multicellular organism growth
negative regulation of apoptotic process
positive regulation of catalytic activity
positive regulation of axon extension
negative regulation of organ growth
positive regulation of transferase activity
positive regulation of lyase activity
positive regulation of oxidoreductase activity
iron ion homeostasis
oxidation-reduction process
cellular response to hydrogen peroxide
negative regulation of release of cytochrome c from mitochondria

Function(s)

ferroxidase activity
ferrous iron binding
ferric iron binding
oxidoreductase activity
enzyme binding
iron chaperone activity
metal ion binding
iron-sulfur cluster binding
2 iron, 2 sulfur cluster binding