158012

• Gene Symbol: Hdac1
• Gene Name: histone deacetylase 1
• Gene Aliases: HD1, Hdac1-ps, MommeD5, RPD3
• Chromosome Location: Chr.4: 129516104 - 129542646 on Build GRCm38
• UniGene ID: Mm.202504
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Hdac1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_008228.2	NP_032254.1	6	580
GenBank mRNA	AK076080.1	-	6	565
	BC092070.1	-	6	575	4217199
	BC092285.1	-	6	580
	BC108371.1	-	6	581	4976514
	U80780.1	-	6	577
	X98207.1	-	6	580

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_053446.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
response to amphetamine
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
protein deacetylation
endoderm development
circadian rhythm
positive regulation of cell proliferation
negative regulation of cell proliferation
epidermal cell differentiation
negative regulation of gene expression
positive regulation of receptor biosynthetic process
chromatin modification
histone deacetylation
hippocampus development
neuron differentiation
positive regulation of interleukin-1 production
positive regulation of tumor necrosis factor production
circadian regulation of gene expression
cellular response to oxidative stress
odontogenesis of dentin-containing tooth
positive regulation of tyrosine phosphorylation of Stat3 protein
embryonic digit morphogenesis
ATP-dependent chromatin remodeling
negative regulation of apoptotic process
negative regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of neuron apoptotic process
negative regulation by host of viral transcription
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
negative regulation of insulin secretion
rhythmic process
positive regulation of oligodendrocyte differentiation
negative regulation of androgen receptor signaling pathway
hair follicle placode formation
eyelid development in camera-type eye
fungiform papilla formation
histone H3 deacetylation
histone H4 deacetylation
negative regulation of canonical Wnt signaling pathway
positive regulation of chemokine (C-X-C motif) ligand 2 production
positive regulation of type B pancreatic cell apoptotic process
negative regulation of peptidyl-lysine acetylation
negative regulation of intrinsic apoptotic signaling pathway

Function(s)

transcription regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
core promoter binding
RNA polymerase II repressing transcription factor binding
RNA polymerase II transcription corepressor activity
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
transcription corepressor activity
histone deacetylase activity
protein binding
transcription factor binding
hydrolase activity
deacetylase activity
enzyme binding
histone deacetylase activity (H3-K14 specific)
nucleosomal DNA binding
NAD-dependent histone deacetylase activity (H3-K14 specific)
histone deacetylase activity (H3-K9 specific)
protein complex binding
protein deacetylase activity
activating transcription factor binding
histone deacetylase activity (H4-K16 specific)
Krueppel-associated box domain binding
histone deacetylase binding
transcription regulatory region DNA binding
NAD-dependent histone deacetylase activity (H3-K9 specific)
NAD-dependent histone deacetylase activity (H4-K16 specific)
protein N-terminus binding
NF-kappaB binding
repressing transcription factor binding
NAD-dependent histone deacetylase activity (H3-K18 specific)