161528

• Gene Symbol: Dnmt1
• Gene Name: DNA methyltransferase (cytosine-5) 1
• Gene Aliases: Cxxc9, Dnmt, Dnmt1o, MCMT, MTase, Met-1, Met1, MommeD2, m.MmuI
• Chromosome Location: Chr.9: 20907205 - 20959888 on Build GRCm38
• UniGene ID: Mm.128580
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Dnmt1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001199431.1	NP_001186360.2	13	1164
	NM_001199432.1	NP_001186361.1	13	1045
	NM_001199433.1	NP_001186362.1	13	1670
	NM_010066.4	NP_034196.5	13	1161
GenBank mRNA	AF036007.1	-	13	1045
	AF036009.1	-	13	1667
	AF162282.1	-	13	1164
	AF175432.1	-	13	1652
	AK136213.1	-	13	946
	AK143578.1	-	13	1045
	AK147143.1	-	13	1056
	BC048148.1	-	13	1031	5706204
	BC053047.1	-	13	1027	5709259
	X14805.1	-	13	1048

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_053354, AB012214, D64060.

Panther Classification:

Molecular Function -

DNA metabolism protein, DNA methyltransferase, nucleic acid metabolism protein

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
DNA methylation
transcription, DNA-templated
regulation of transcription, DNA-templated
metabolic process
maintenance of DNA methylation
DNA methylation on cytosine within a CG sequence
regulation of gene expression
positive regulation of gene expression
gene silencing
chromatin modification
methylation
DNA methylation on cytosine
response to antidepressant
regulation of cell proliferation
DNA hypermethylation
negative regulation of transcription, DNA-templated
S-adenosylhomocysteine metabolic process
S-adenosylmethioninamine metabolic process
S-adenosylmethionine metabolic process
positive regulation of histone H3-K4 methylation
negative regulation of histone H3-K9 methylation
cellular response to amino acid stimulus
cellular response to transforming growth factor beta stimulus
C-5 methylation of cytosine

Function(s)

DNA binding
chromatin binding
double-stranded DNA binding
RNA binding
catalytic activity
DNA (cytosine-5-)-methyltransferase activity
protein binding
transcription factor binding
methyltransferase activity
zinc ion binding
methyl-CpG binding
DNA-methyltransferase activity
transferase activity
protein domain specific binding
estrogen receptor binding
histone deacetylase binding
unmethylated CpG binding
metal ion binding
DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates