172683

• Gene Symbol: Bbc3
• Gene Name: BCL2 binding component 3
• Gene Aliases: PUMA, PUMA/JFY1
• Chromosome Location: Chr.7: 16308321 - 16318334 on Build GRCm38
• UniGene ID: Mm.7660
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Bbc3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_133234.2	NP_573497.1	4	1576
GenBank mRNA	AF332560.1	-	4	1520
	BC044782.2	-	4	1541
	BC060370.1	-	4	1506

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_001127241, NM_001127240, NM_001127242, NM_014417, U82987, and others.
This siRNA also targets the following transcripts in Rat: NM_173837, AY157758.

Gene Ontology Categories:

Process(es)

release of cytochrome c from mitochondria
apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
cellular response to DNA damage stimulus
determination of adult lifespan
negative regulation of cell growth
positive regulation of protein homooligomerization
negative regulation of endoplasmic reticulum calcium ion concentration
response to endoplasmic reticulum stress
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
positive regulation of apoptotic process
positive regulation of neuron apoptotic process
negative regulation of growth
release of sequestered calcium ion into cytosol
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
positive regulation of thymocyte apoptotic process
cellular response to ionizing radiation
intrinsic apoptotic signaling pathway by p53 class mediator
positive regulation of release of cytochrome c from mitochondria
apoptotic signaling pathway
execution phase of apoptosis
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
toxin transport
positive regulation of cysteine-type endopeptidase activity
positive regulation of intrinsic apoptotic signaling pathway

Function(s)

protein binding