175197

• Gene Symbol: Nedd4l
• Gene Name: neural precursor cell expressed, developmentally down-regulated gene 4-like
• Gene Aliases: 1300012C07Rik, Nedd4-2, Nedd4b
• Chromosome Location: Chr.18: 64887756 - 65217826 on Build GRCm38
• UniGene ID: Mm.98668
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Nedd4l
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001114386.1	NP_001107858.1	10, 11	1116
	NM_031881.2	NP_114087.2	9, 10	1165
GenBank mRNA	AF277232.1	-	9, 10	798
	AK004969.1	-	9, 10	858
	AK031842.1	-	9, 10	846
	AK042621.1	-	10, 11	799
	AK122283.1	-	9, 10	968
	AK163497.1	-	8, 9	646
	AK197688.1	-	1, 2	27
	BC039746.1	-	9, 10	809	3157137
	BC071210.1	-	9, 10	786	4972426
	BC082281.1	-	9, 10	835

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_001243960, NM_015277, NM_001144968, NM_001144967, NM_001144969, and others.
This siRNA also targets the following transcripts in Rat: NM_001008300, GQ160815, GQ160816.

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

negative regulation of systemic arterial blood pressure
regulation of membrane depolarization
protein monoubiquitination
response to salt stress
response to metal ion
positive regulation of sodium ion transport
negative regulation of sodium ion transport
protein ubiquitination
regulation of ion transmembrane transport
regulation of membrane potential
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
positive regulation of protein catabolic process
regulation of membrane repolarization
protein K48-linked ubiquitination
ventricular cardiac muscle cell action potential
regulation of potassium ion transmembrane transporter activity
negative regulation of potassium ion transmembrane transporter activity
negative regulation of potassium ion transmembrane transport
negative regulation of sodium ion transmembrane transport
positive regulation of dendrite extension
negative regulation of protein localization to cell surface
negative regulation of sodium ion transmembrane transporter activity
regulation of bicellular tight junction assembly
positive regulation of cation channel activity
positive regulation of caveolin-mediated endocytosis

Function(s)

ubiquitin-protein transferase activity
protein binding
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
potassium channel regulator activity
ligase activity
sodium channel regulator activity
ribosomal S6-glutamic acid ligase activity
potassium channel inhibitor activity
sodium channel inhibitor activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
ion channel binding
ubiquitin protein ligase activity
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity