17562

• Gene Symbol: RAPGEF3
• Gene Name: Rap guanine nucleotide exchange factor 3
• Gene Aliases: CAMP-GEFI, EPAC, EPAC1, HSU79275, bcm910
• Chromosome Location: Chr.12: 47734670 - 47759106 on Build GRCh38
• UniGene ID: Hs.8578
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: RAPGEF3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001098531.2	NP_001092001.1	28	3532
	NM_001098532.2	NP_001092002.1	27	3296
	NM_006105.5	NP_006096.2	28	3066
	XM_005268571.3	XP_005268628.1	27	3042
	XM_011537752.1	XP_011536054.1	28	3549
	XM_011537755.1	XP_011536057.1	28	3111
	XM_011537758.2	XP_011536060.1	28	3161
GenBank mRNA	AK055502.1	-	10	1847
	AK074444.1	-	12	2224
	AK092448.1	-	28	3504
	AK125545.1	-	24	2549
	AK290230.1	-	29	3197
	BC017728.1	-	28	3146	4414360
	BC092404.1	-	28	3135	6181000

More Information

Panther Classification:

Molecular Function -

guanyl-nucleotide exchange factor

Gene Ontology Categories:

Process(es)

angiogenesis
signal transduction
brain development
cell proliferation
negative regulation of cardiac muscle cell apoptotic process
positive regulation of smooth muscle cell migration
cAMP-mediated signaling
spinal cord development
positive regulation of cAMP catabolic process
Rap protein signal transduction
negative regulation of collagen biosynthetic process
positive regulation of peptidyl-serine phosphorylation
negative regulation of syncytium formation by plasma membrane fusion
response to nicotine
cellular response to drug
positive regulation of GTPase activity
positive regulation of angiogenesis
positive regulation of cell size
positive regulation of transcription from RNA polymerase II promoter
positive regulation of protein export from nucleus
regulation of insulin secretion
positive regulation of stress fiber assembly
positive regulation of syncytium formation by plasma membrane fusion
artery development
establishment of endothelial barrier
cellular response to cAMP
cellular response to transforming growth factor beta stimulus
liver regeneration
positive regulation of protein acetylation
positive regulation of GTP binding
positive regulation of calcium ion transmembrane transport
positive regulation of hydrogen:potassium-exchanging ATPase activity
cellular response to L-dopa
dorsal root ganglion development
regulation of actin cytoskeleton reorganization
positive regulation of actin cytoskeleton reorganization
regulation of histone H3-K9 acetylation

Function(s)

guanyl-nucleotide exchange factor activity
protein binding
Rap guanyl-nucleotide exchange factor activity
protein domain specific binding
cAMP binding
ion channel binding