184407

• Gene Symbol: Chek2
• Gene Name: checkpoint kinase 2
• Gene Aliases: CHK2, Cds1, HUCDS1, Rad53
• Chromosome Location: Chr.5: 110839791 - 110874140 on Build GRCm38
• UniGene ID: Mm.279308
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Chek2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_016681.3	NP_057890.1	3	418
GenBank mRNA	AF086905.1	-	2	379
	AK044913.1	-	3	419
	AK170235.1	-	3	453
	BC056617.1	-	3	442	4977960

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_053677, XM_006249521, XM_006249520, XM_006249519, XM_006249518, and others.

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

DNA damage checkpoint
G2/M transition of mitotic cell cycle
replicative cell aging
DNA repair
double-strand break repair
transcription, DNA-templated
regulation of transcription, DNA-templated
protein phosphorylation
apoptotic process
cellular response to DNA damage stimulus
DNA damage induced protein phosphorylation
cell cycle
mitotic nuclear division
intrinsic apoptotic signaling pathway in response to DNA damage
response to gamma radiation
phosphorylation
regulation of protein catabolic process
signal transduction in response to DNA damage
cellular protein catabolic process
positive regulation of transcription, DNA-templated
protein autophosphorylation
protein stabilization
cell division
signal transduction involved in intra-S DNA damage checkpoint
mitotic spindle assembly

Function(s)

nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
protein kinase binding
ubiquitin protein ligase binding
identical protein binding
protein homodimerization activity
metal ion binding