185305

• Gene Symbol: Tdp2
• Gene Name: tyrosyl-DNA phosphodiesterase 2
• Gene Aliases: D13Ertd656e, Ttrap
• Chromosome Location: Chr.13: 24831647 - 24842153 on Build GRCm38
• UniGene ID: Mm.427162
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Tdp2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_019551.2	NP_062424.1	7	1047
GenBank mRNA	AJ251328.1	-	7	1021
	AK009089.1	-	7	1021
	AK135925.1	-	7	1059
	AK167707.1	-	6	843
	BC132511.1	-	7	1010	40130788
	BC132513.1	-	7	1010	40130790
	BC145334.1	-	6	839

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001034947, BC101920.

Gene Ontology Categories:

Process(es)

DNA repair
double-strand break repair
cellular response to DNA damage stimulus
nucleic acid phosphodiester bond hydrolysis

Function(s)

magnesium ion binding
single-stranded DNA binding
cyclic-nucleotide phosphodiesterase activity
3',5'-cyclic-AMP phosphodiesterase activity
calmodulin-dependent cyclic-nucleotide phosphodiesterase activity
cGMP-stimulated cyclic-nucleotide phosphodiesterase activity
cGMP-inhibited cyclic-nucleotide phosphodiesterase activity
photoreceptor cyclic-nucleotide phosphodiesterase activity
nuclease activity
endonuclease activity
phosphoric diester hydrolase activity
hydrolase activity
manganese ion binding
tyrosyl-RNA phosphodiesterase activity
7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity
metal ion binding
inositol phosphosphingolipid phospholipase activity
inositol phosphorylceramide phospholipase activity
mannosyl-inositol phosphorylceramide phospholipase activity
mannosyl-diinositol phosphorylceramide phospholipase activity
5'-tyrosyl-DNA phosphodiesterase activity