190673

• Gene Symbol: Chek1
• Gene Name: checkpoint kinase 1
• Gene Aliases: -
• Chromosome Location: Chr.8: 39181162 - 39202647 on Build Rnor_6.0
• UniGene ID: Rn.33267
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Chek1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_080400.1	NP_536325.1	4	379
	XM_008766042.1	XP_008764264.1	4	1512
	XM_008766043.1	XP_008764265.1	4	449
GenBank mRNA	AF414135.1	-	4	379
	AF443592.1	-	4	377

More Information

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

DNA damage checkpoint
G2/M transition of mitotic cell cycle
DNA repair
protein phosphorylation
cellular response to DNA damage stimulus
DNA damage induced protein phosphorylation
regulation of gene expression
regulation of double-strand break repair via homologous recombination
regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage
negative regulation of G2/M transition of mitotic cell cycle
peptidyl-threonine phosphorylation
histone H3-T11 phosphorylation
regulation of cell proliferation
negative regulation of mitotic nuclear division
regulation of mitotic centrosome separation
chromatin-mediated maintenance of transcription
cellular response to mechanical stimulus
cellular response to organic substance
cellular response to caffeine
negative regulation of DNA biosynthetic process
regulation of histone H3-K9 acetylation

Function(s)

protein kinase activity
protein serine/threonine kinase activity
protein binding
ATP binding
histone kinase activity (H3-T11 specific)