194

• Gene Symbol: FLT4
• Gene Name: fms related tyrosine kinase 4
• Gene Aliases: FLT-4, FLT41, LMPH1A, PCL, VEGFR-3, VEGFR3
• Chromosome Location: Chr.5: 180601506 - 180650298 on Build GRCh38
• UniGene ID: Hs.646917
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: FLT4
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_002020.4	NP_002011.2	28	3839
	NM_182925.4	NP_891555.2	28	3839
	XM_011534478.2	XP_011532780.1	28	4217
	XM_011534484.2	XP_011532786.1	26	3397
	XM_017009263.1	XP_016864752.1	28	4223
	XM_017009264.1	XP_016864753.1	28	4223
	XM_017009265.1	XP_016864754.1	28	4224
	XM_017009266.1	XP_016864755.1	28	4218
	XM_017009267.1	XP_016864756.1	28	4218
	XM_017009268.1	XP_016864757.1	28	3782
GenBank mRNA	AB209637.1	-	20	4130
	AK291679.1	-	28	3815
	AK309910.1	-	28	3815
	AY233382.1	-	28	3780
	AY233383.1	-	28	3780
	U43143.1	-	28	3790
	X68203.1	-	28	3779
	X69878.1	-	28	3781

More Information

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

positive regulation of protein phosphorylation
positive regulation of endothelial cell proliferation
vasculature development
lymph vessel development
lymphangiogenesis
sprouting angiogenesis
transmembrane receptor protein tyrosine kinase signaling pathway
positive regulation of cell proliferation
positive regulation of vascular endothelial growth factor production
positive regulation of endothelial cell migration
peptidyl-tyrosine phosphorylation
cellular response to vascular endothelial growth factor stimulus
vascular endothelial growth factor signaling pathway
negative regulation of apoptotic process
positive regulation of MAPK cascade
positive regulation of JNK cascade
protein autophosphorylation
vascular endothelial growth factor receptor signaling pathway
blood vessel morphogenesis
regulation of blood vessel remodeling
positive regulation of ERK1 and ERK2 cascade
positive regulation of protein kinase C signaling

Function(s)

transmembrane receptor protein tyrosine kinase activity
vascular endothelial growth factor-activated receptor activity
protein binding
ATP binding
growth factor binding
protein phosphatase binding