195778

• Gene Symbol: Mapk1
• Gene Name: mitogen activated protein kinase 1
• Gene Aliases: Erk2
• Chromosome Location: Chr.11: 88203785 - 88273288 on Build Rnor_6.0
• UniGene ID: Rn.34914
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Mapk1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_053842.1	NP_446294.1	2	450
	XM_006248658.2	XP_006248720.1	2	487
	XM_006248659.2	XP_006248721.1	2	487
	XM_008768848.1	XP_008767070.1	2	487
GenBank mRNA	FQ211642.1	-	2	490
	M64300.1	-	2	450

More Information

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

MAPK cascade
MAPK import into nucleus
protein phosphorylation
apoptotic process
cellular response to DNA damage stimulus
signal transduction
positive regulation of cell proliferation
response to toxic substance
organ morphogenesis
positive regulation of peptidyl-threonine phosphorylation
peptidyl-serine phosphorylation
peptidyl-threonine phosphorylation
sensory perception of pain
cytosine metabolic process
positive regulation of cell migration
regulation of protein stability
lipopolysaccharide-mediated signaling pathway
response to lipopolysaccharide
regulation of stress-activated MAPK cascade
mammary gland epithelial cell proliferation
intracellular signal transduction
ERBB signaling pathway
response to exogenous dsRNA
response to estrogen
negative regulation of cell differentiation
positive regulation of translation
positive regulation of transcription, DNA-templated
T cell receptor signaling pathway
B cell receptor signaling pathway
regulation of cytoskeleton organization
long-term synaptic potentiation
lung morphogenesis
trachea formation
labyrinthine layer blood vessel development
ERK1 and ERK2 cascade
response to epidermal growth factor
cellular response to organic substance
caveolin-mediated endocytosis
regulation of Golgi inheritance
cellular response to granulocyte macrophage colony-stimulating factor stimulus
regulation of early endosome to late endosome transport

Function(s)

phosphotyrosine binding
protein kinase activity
protein serine/threonine kinase activity
MAP kinase activity
protein binding
ATP binding
transcription factor binding
RNA polymerase II carboxy-terminal domain kinase activity
kinase activity
protein kinase binding
phosphatase binding
mitogen-activated protein kinase kinase kinase binding