195

• Gene Symbol: FLT4
• Gene Name: fms related tyrosine kinase 4
• Gene Aliases: FLT-4, FLT41, LMPH1A, PCL, VEGFR-3, VEGFR3
• Chromosome Location: Chr.5: 180601506 - 180650298 on Build GRCh38
• UniGene ID: Hs.646917
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: FLT4
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_002020.4	NP_002011.2	3	369
	NM_182925.4	NP_891555.2	3	369
	XM_011534478.2	XP_011532780.1	3	747
	XM_017009263.1	XP_016864752.1	3	753
	XM_017009264.1	XP_016864753.1	3	753
	XM_017009265.1	XP_016864754.1	3	754
	XM_017009266.1	XP_016864755.1	3	748
	XM_017009267.1	XP_016864756.1	3	748
	XM_017009268.1	XP_016864757.1	3	312
GenBank mRNA	AK291679.1	-	3	345
	AK309910.1	-	3	345
	AY233382.1	-	3	310
	AY233383.1	-	3	310
	DB455035.2	-	3	369
	EU826564.1	-	3	290
	EU826565.1	-	3	290
	EU826566.1	-	3	290
	U43143.1	-	3	320
	X68203.1	-	3	309
	X69878.1	-	3	311

More Information

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

positive regulation of protein phosphorylation
positive regulation of endothelial cell proliferation
vasculature development
lymph vessel development
lymphangiogenesis
sprouting angiogenesis
transmembrane receptor protein tyrosine kinase signaling pathway
positive regulation of cell proliferation
positive regulation of vascular endothelial growth factor production
positive regulation of endothelial cell migration
peptidyl-tyrosine phosphorylation
cellular response to vascular endothelial growth factor stimulus
vascular endothelial growth factor signaling pathway
negative regulation of apoptotic process
positive regulation of MAPK cascade
positive regulation of JNK cascade
protein autophosphorylation
vascular endothelial growth factor receptor signaling pathway
blood vessel morphogenesis
regulation of blood vessel remodeling
positive regulation of ERK1 and ERK2 cascade
positive regulation of protein kinase C signaling

Function(s)

transmembrane receptor protein tyrosine kinase activity
vascular endothelial growth factor-activated receptor activity
protein binding
ATP binding
growth factor binding
protein phosphatase binding