201415

• Gene Symbol: Ptprc
• Gene Name: protein tyrosine phosphatase, receptor type, C
• Gene Aliases: CD45, L-CA, Lca, RT7, T200
• Chromosome Location: Chr.13: 55061561 - 55174150 on Build Rnor_6.0
• UniGene ID: Rn.90166
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Ptprc
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001109887.1	NP_001103357.1	10	1000
	NM_001109888.1	NP_001103358.1	10	979
	NM_001109889.1	NP_001103359.1	10	976
	NM_001109890.1	NP_001103360.1	9	853
	NM_138507.2	NP_612516.2	12	1249
	XM_006249910.2	XP_006249972.1	12	1343
	XM_006249912.2	XP_006249974.1	11	1177
	XM_008769534.1	XP_008767756.1	11	1180
GenBank mRNA	AF251010.1	-	8	727
	M10072.1	-	4	592
	Y00065.1	-	10	1078

More Information

Panther Classification:

Molecular Function -

extracellular matrix protein, protein phosphatase, protein modifying enzyme

Gene Ontology Categories:

Process(es)

activation of MAPK activity
negative regulation of T cell mediated cytotoxicity
positive regulation of T cell mediated cytotoxicity
negative regulation of cytokine-mediated signaling pathway
hematopoietic progenitor cell differentiation
immunoglobulin biosynthetic process
positive regulation of T cell mediated immunity
regulation of humoral immune response mediated by circulating immunoglobulin
positive regulation of humoral immune response mediated by circulating immunoglobulin
negative regulation of protein kinase activity
protein dephosphorylation
negative regulation of cell adhesion involved in substrate-bound cell migration
leukocyte cell-cell adhesion
response to gamma radiation
dephosphorylation
B cell differentiation
T cell differentiation
positive regulation of B cell proliferation
negative regulation of protein autophosphorylation
heterotypic cell-cell adhesion
peptidyl-tyrosine dephosphorylation
T cell proliferation
B cell proliferation
positive regulation of T cell proliferation
positive regulation of MAPK cascade
cell cycle phase transition
positive thymic T cell selection
negative thymic T cell selection
regulation of B cell differentiation
positive regulation of T cell differentiation
positive regulation of gamma-delta T cell differentiation
positive regulation of alpha-beta T cell proliferation
positive regulation of isotype switching to IgG isotypes
bone marrow development
stem cell development
negative regulation of peptidyl-tyrosine phosphorylation
T cell receptor signaling pathway
B cell receptor signaling pathway
regulation of B cell receptor signaling pathway
positive regulation of antigen receptor-mediated signaling pathway
release of sequestered calcium ion into cytosol
defense response to virus
regulation of cell cycle
positive regulation of hematopoietic stem cell migration
positive regulation of stem cell proliferation
regulation of extrinsic apoptotic signaling pathway
positive regulation of extrinsic apoptotic signaling pathway

Function(s)

protein tyrosine phosphatase activity
transmembrane receptor protein tyrosine phosphatase activity
protein binding
heparin binding
protein kinase regulator activity
protein kinase binding
heparan sulfate proteoglycan binding