20973

• Gene Symbol: RBX1
• Gene Name: ring-box 1
• Gene Aliases: BA554C12.1, RNF75, ROC1
• Chromosome Location: Chr.22: 40951347 - 40973015 on Build GRCh38
• UniGene ID: Hs.474949
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: RBX1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_014248.3	NP_055063.1	2	197
GenBank mRNA	AF085906.1	-	2	126
	AF140598.1	-	2	151
	AF142059.1	-	2	145
	AK315722.1	-	2	156
	AY099360.1	-	2	108
	BC001466.2	-	2	150	3138751
	BC017370.1	-	2	167
	CR456560.1	-	2	163
	DA353856.1	-	2	197

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001034135, BC100258.
This siRNA also targets the following transcripts in Mouse: NM_019712, BC027396, CJ082632, AF140599, AK183716, and others.

Panther Classification:

Molecular Function -

ubiquitin-protein ligase, protein modifying enzyme

Gene Ontology Categories:

Process(es)

MAPK cascade
protein polyubiquitination
nucleotide-excision repair, DNA damage recognition
nucleotide-excision repair, DNA duplex unwinding
transcription-coupled nucleotide-excision repair
nucleotide-excision repair, preincision complex stabilization
nucleotide-excision repair, preincision complex assembly
nucleotide-excision repair, DNA incision, 3'-to lesion
nucleotide-excision repair, DNA incision, 5'-to lesion
protein monoubiquitination
viral process
Wnt signaling pathway
protein ubiquitination
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
nucleotide-excision repair, DNA incision
DNA damage response, detection of DNA damage
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
protein neddylation
regulation of transcription from RNA polymerase II promoter in response to hypoxia
global genome nucleotide-excision repair
negative regulation of canonical Wnt signaling pathway

Function(s)

ubiquitin-protein transferase activity
protein binding
zinc ion binding
ligase activity
NEDD8 transferase activity
ubiquitin protein ligase binding
protein complex binding
ubiquitin-ubiquitin ligase activity
ubiquitin protein ligase activity
cullin family protein binding