213748

• Gene Symbol: SMURF1
• Gene Name: SMAD specific E3 ubiquitin protein ligase 1
• Gene Aliases: -
• Chromosome Location: Chr.7: 99027435 - 99144120 on Build GRCh38
• UniGene ID: Hs.189329
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: SMURF1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001199847.1	NP_001186776.1	3	500
	NM_020429.2	NP_065162.1	3	500
	NM_181349.2	NP_851994.1	3	500
	XM_017012457.1	XP_016867946.1	3	498
GenBank mRNA	AB046845.1	-	3	468
	AF199364.2	-	3	133
	AF464850.1	-	3	160
	BC136804.1	-	3	377	9020794
	BC144414.1	-	3	377	9052935
	BC152468.1	-	3	468	8862605
	DB727777.1	-	3	502

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001109598, XM_006248882, XM_008769002.
This siRNA also targets the following transcripts in Mouse: NM_001038627, NM_029438, AK154491, BC029097.

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

protein polyubiquitination
positive regulation of defense response to virus by host
protein export from nucleus
transforming growth factor beta receptor signaling pathway
ectoderm development
protein ubiquitination
cell differentiation
negative regulation of ossification
BMP signaling pathway
negative regulation of transforming growth factor beta receptor signaling pathway
negative regulation of BMP signaling pathway
ubiquitin-dependent SMAD protein catabolic process
receptor catabolic process
protein localization to cell surface
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
Wnt signaling pathway, planar cell polarity pathway
engulfment of target by autophagosome
protein targeting to vacuole involved in autophagy
protein targeting to plasma membrane
mitophagy in response to mitochondrial depolarization
positive regulation of dendrite extension
positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Function(s)

ubiquitin-protein transferase activity
protein binding
phospholipid binding
ligase activity
activin binding
ubiquitin protein ligase activity
I-SMAD binding
R-SMAD binding