213866

• Gene Symbol: AURKA
• Gene Name: aurora kinase A
• Gene Aliases: AIK, ARK1, AURA, BTAK, PPP1R47, STK15, STK6, STK7
• Chromosome Location: Chr.20: 56369389 - 56392337 on Build GRCh38
• UniGene ID: Hs.250822
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: AURKA
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001323303.1	NP_001310232.1	7	1179
	NM_001323304.1	NP_001310233.1	7	942
	NM_001323305.1	NP_001310234.1	8	1052
	NM_003600.3	NP_003591.2	6	1069
	NM_198433.2	NP_940835.1	8	1277
	NM_198434.2	NP_940836.1	7	968
	NM_198435.2	NP_940837.1	6	858
	NM_198436.2	NP_940838.1	7	954
	NM_198437.2	NP_940839.1	6	844
	XM_017028034.1	XP_016883523.1	8	1399
	XM_017028035.1	XP_016883524.1	6	759
GenBank mRNA	AF008551.1	-	5	669
	AF011468.1	-	6	925
	AK301769.1	-	6	531
	AK312776.1	-	6	736
	BC001280.1	-	7	801	3456017
	BC002499.2	-	6	797	3051177
	BC006423.1	-	6	694	3532438
	BC027464.1	-	7	836	4449474
	BM458030.1	-	7	869
	BQ435059.1	-	6	690
	BU171303.1	-	6	791
	D84212.1	-	7	835

More Information

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

G2/M transition of mitotic cell cycle
meiotic spindle organization
protein phosphorylation
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
spindle organization
mitotic spindle organization
spindle assembly involved in female meiosis I
mitotic nuclear division
mitotic centrosome separation
anterior/posterior axis specification
anaphase-promoting complex-dependent catabolic process
regulation of protein stability
negative regulation of protein binding
response to estradiol
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
regulation of cytokinesis
histone-serine phosphorylation
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
negative regulation of apoptotic process
positive regulation of mitotic nuclear division
regulation of centrosome cycle
protein autophosphorylation
cell division
centrosome localization
protein localization to centrosome
positive regulation of oocyte maturation
regulation of signal transduction by p53 class mediator
neuron projection extension

Function(s)

protein kinase activity
protein serine/threonine kinase activity
protein serine/threonine/tyrosine kinase activity
protein binding
ATP binding
protein kinase binding
ubiquitin protein ligase binding
histone serine kinase activity