214562

• Gene Symbol: ARHGEF2
• Gene Name: Rho/Rac guanine nucleotide exchange factor 2
• Gene Aliases: GEF, GEF-H1, GEFH1, LFP40, P40
• Chromosome Location: Chr.1: 155946839 - 155991263 on Build GRCh38
• UniGene ID: Hs.743352
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: ARHGEF2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001162383.1	NP_001155855.1	5, 6	584
	NM_001162384.1	NP_001155856.1	5, 6	584
	NM_004723.3	NP_004714.2	5, 6	512
	XM_005245587.2	XP_005245644.1	5, 6	637
	XM_005245588.2	XP_005245645.1	5, 6	637
	XM_005245589.4	XP_005245646.1	5, 6	790
	XM_005245590.3	XP_005245647.1	5, 6	512
	XM_005245591.3	XP_005245648.1	6, 7	628
	XM_005245592.2	XP_005245649.1	5, 6	781
	XM_005245593.4	XP_005245650.1	5, 6	512
	XM_005245594.2	XP_005245651.1	5, 6	1498
	XM_006711622.3	XP_006711685.1	5, 6	1775
	XM_006711623.3	XP_006711686.1	4, 5	511
	XM_006711624.3	XP_006711687.1	4, 5	538
	XM_006711625.3	XP_006711688.1	4, 5	444
	XM_006711626.2	XP_006711689.1	4, 5	1430
	XM_011510136.2	XP_011508438.2	9, 10	1196
	XM_011510137.2	XP_011508439.2	9, 10	1196
	XM_011510139.2	XP_011508441.1	9, 10	1196
	XM_011510141.2	XP_011508443.1	5, 6	1314
	XM_017002794.1	XP_016858283.1	9, 10	1196
	XM_017002795.1	XP_016858284.1	5, 6	531
	XM_017002796.1	XP_016858285.1	5, 6	1775
	XM_017002797.1	XP_016858286.1	5, 6	515
	XM_017002798.1	XP_016858287.1	4, 5	1707
	XM_017002799.1	XP_016858288.1	4, 5	511
GenBank mRNA	AB014551.3	-	9, 10	855
	AF486838.1	-	5, 6	466
	AK295924.1	-	5, 6	781
	AK304548.1	-	8, 9	921
	AL512715.1	-	5, 6	497
	BC020567.1	-	5, 6	566	4157775
	BT007407.1	-	4, 5	385
	U72206.1	-	5, 6	568

More Information

Gene Ontology Categories:

Process(es)

establishment of mitotic spindle orientation
cell morphogenesis
intracellular protein transport
actin filament organization
negative regulation of microtubule depolymerization
mitotic nuclear division
positive regulation of interleukin-6 production
positive regulation of tumor necrosis factor production
regulation of Rho protein signal transduction
intracellular signal transduction
regulation of cell proliferation
positive regulation of apoptotic process
positive regulation of GTPase activity
innate immune response
positive regulation of transcription from RNA polymerase II promoter
positive regulation of peptidyl-tyrosine phosphorylation
negative regulation of neurogenesis
regulation of small GTPase mediated signal transduction
positive regulation of NF-kappaB transcription factor activity
cell division
negative regulation of necroptotic process
cellular response to muramyl dipeptide
cellular response to tumor necrosis factor
cellular hyperosmotic response
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress

Function(s)

guanyl-nucleotide exchange factor activity
Rho guanyl-nucleotide exchange factor activity
protein binding
microtubule binding
transcription factor binding
zinc ion binding
Rho GTPase binding
Rac guanyl-nucleotide exchange factor activity
Rac GTPase binding